sphingosine 1-phosphate

N-acylsphingosine amidohydrolase 1 ; Homo sapiens







14 Article(s)
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1 33357194 Acid ceramidase, a double-edged sword in cancer aggression: A minireview. 2020 Dec 23 5
2 29023248 Anticancer effect of acid ceramidase inhibitor ceranib-2 in human breast cancer cell lines MCF-7, MDA MB-231 by the activation of SAPK/JNK, p38 MAPK apoptotic pathways, inhibition of the Akt pathway, downregulation of ERα. 2018 Jan 1
3 26553872 Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. 2016 Jan 29 3
4 25888580 Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP. 2015 Oct 2
5 26188095 Targeting ceramide metabolic pathway induces apoptosis in human breast cancer cell lines. 2015 Aug 28 1
6 23423838 Acid ceramidase as a therapeutic target in metastatic prostate cancer. 2013 May 2
7 23732709 Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling. 2013 Jun 3 2
8 23939396 Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells. 2013 Dec 1
9 24098536 Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. 2013 3
10 22322590 Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B. 2012 Nov 1 2
11 21116286 Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide. 2011 Mar 1
12 20502000 Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. 2010 1
13 18691012 Molecular targeting of acid ceramidase: implications to cancer therapy. 2008 Aug 2
14 17264167 Acid ceramidase is a novel factor required for early embryo survival. 2007 May 4