Title : Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide.

Pub. Date : 2011 Mar

PMID : 21116286






1 Functional Relationships(s)
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1 The consequence of AC overexpression is the ability to convert ceramide, which is often produced as a proapoptotic response to stress, to sphingosine, which can then be converted to the prosurvival molecule sphingosine-1-phosphate. sphingosine 1-phosphate N-acylsphingosine amidohydrolase 1 Homo sapiens