Pub. Date : 2016 Jan 29
PMID : 26553872
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acid ceramidase (AC) is a lysosomal cysteine amidase that controls sphingolipid signaling by lowering the levels of ceramides and concomitantly increasing those of sphingosine and its bioactive metabolite, sphingosine 1-phosphate. | sphingosine 1-phosphate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |
| 2 | Acid ceramidase (AC) is a lysosomal cysteine amidase that controls sphingolipid signaling by lowering the levels of ceramides and concomitantly increasing those of sphingosine and its bioactive metabolite, sphingosine 1-phosphate. | sphingosine 1-phosphate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |
| 3 | AC inhibition increased cellular ceramide levels, decreased sphingosine 1-phosphate levels, and acted synergistically with several, albeit not all, antitumoral agents. | sphingosine 1-phosphate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |