Phenobarbital

cytochrome P450, family 2, subfamily g, polypeptide 1 ; Rattus norvegicus







542 Article(s)
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1 25786523 Dehydroepiandrosterone sulfate and cytochrome P450 inducers alleviate fatty liver in male rats fed an orotic acid-supplemented diet. 2015 Apr 1
2 21968144 Proteome studies on liver tissue in a phenobarbital-induced rat model. 2011 Nov 30 3
3 20166883 Cytochrome P450 induction by phenobarbital exacerbates warm hepatic ischemia-reperfusion injury in rat livers. 2010 Apr 1
4 18827444 Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats. 2008 Oct 1
5 21783825 Tissue-specific induction of the carcinogen-inducible cytochrome P450 isoforms in the gastrointestinal tract. 2007 Nov 1
6 16724577 In vitro investigations on the differential pro-oxidant and/or antioxidant properties of cyclosporin A and tacrolimus in human and rat liver microsomes. 2006 May 2
7 15666291 Reductase-mediated metabolism of motexafin gadolinium (Xcytrin) in rat and human liver subcellular fractions and purified enzyme preparations. 2005 Mar 2
8 15713442 Induction of cytochrome P450 isozymes by phenobarbital in pregnant rat and fetal livers and placenta. 2005 Apr 3
9 15926192 Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous DA-8159, a new erectogenic, in rats. 2005 Sep 2
10 23923552 Effect of phenobarbitone on cytochrome P450 activity and chlorpyrifos and 3,5,6-trichloropyridinol levels in liver and serum in rat. 2005 Aug 2
11 12712632 Cytochrome P-4503A1 catalyzes the formation of MA1 from territrem a in liver microsomes of 7-week-old female Wistar rats. 2003 Mar 14 1
12 12837975 Phenobarbital-imprinted overinduction of adult constituent CYP isoforms. 2003 Aug 1
13 11158222 Downregulation of hepatic cytochrome P450 in chronic renal failure. 2001 Feb 2
14 10718121 Metabolite-intermediate complexation and inhibition of microsomal CYP3A in rat liver by diltiazem. 2000 Feb 1
15 10825474 Effect of phenobarbital on intralobular expression of CYP2B1/2 in livers of rats: difference in the expression between single and repetitive administrations. 2000 Jul 15 6
16 10859158 Role of C-5 chiral center in R-(+)-pulegone-mediated hepatotoxicity: metabolic disposition and toxicity of 5, 5-dimethyl-2-(1-Methylethylidene)-cyclohexanone in rats. 2000 Jul 2
17 10885034 [Participation of the cytochrome P450-dependent biotransformation system in realizing the toxic effects of acrylamide]. 2000 Mar-Apr 1
18 11025406 Cytochrome P450 activity and endothelial dysfunction in insulin resistance. 2000 Sep-Oct 1
19 11137894 Apolipoprotein A-I gene expression is upregulated by polychlorinated biphenyls in rat liver. 2000 Nov 1
20 11180194 Effects of enzyme inducers and inhibitor on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats. 2000 May 2
21 11180198 Effects of enzyme inducers or inhibitors on the pharmacokinetics of intravenous parathion in rats. 2000 Jul 2
22 9974185 Induction of hepatic CYP2B in foetal and neonatal rats after maternal administration of phenobarbital. 1999 Jan 2
23 10064562 Effect of cryopreservation on cytochrome P-450 enzyme induction in cultured rat hepatocytes. 1999 Mar 2
24 10096772 Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes. 1999 Feb 26 4
25 10348806 Mechanism-based inactivation of rat liver cytochrome P-450 2B1 by 2-methoxy-5-nitrobenzyl bromide. 1999 Jun 1
26 10405987 Effect of enzyme imprinting of liver microsomal monooxygenases upon lifespan of rats. 1999 Jun 1 1
27 10462055 Cytochrome P450 destruction by quinones: comparison of effects in rat and human liver microsomes. 1999 Aug 1 2
28 10598750 Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate. 1999 Nov 2
29 9537282 Comparative pharmacodynamics of CYP2B induction by DDT, DDE, and DDD in male rat liver and cultured rat hepatocytes. 1998 Mar 27 1
30 9742071 Effect of 3-methylcholanthrene administration on expression of cytochrome P-450 isoforms induced by phenobarbital in rat hepatocytes. 1998 Oct 1
31 9781726 Nitric oxide synthase inhibition and the induction of cytochrome P-450 affect heme oxygenase-1 messenger RNA expression after partial hepatectomy and acute inflammation in rats. 1998 Oct 1
32 9113263 Antipyrine and aminopyrine induce acetaldehyde accumulation from ethanol in isolated hepatocytes. 1997 Apr 1
33 9144458 Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes. 1997 Apr 1
34 9179985 In vitro metabolism of the new insecticide flupyrazofos by rat liver microsomes. 1997 May 1
35 9206565 [A method for stimulating the protective mechanisms of the gastric mucosa in peptic ulcer]. 1997 Mar-Apr 1
36 9210976 Effect of phenobarbital, 3-methylcholanthrene, and chloramphenicol pretreatment on the pharmacokinetics and pharmacodynamics of azosemide in rats. 1997 Jul 1
37 9275273 Sex differences in biotransformation of the xenobiotic p-nitroanisole in isolated rat hepatocyte under the influence of phenobarbital. 1997 Apr 1
38 9328175 Cytochrome P450 mediated bioactivation of methyleugenol to 1'-hydroxymethyleugenol in Fischer 344 rat and human liver microsomes. 1997 Sep 1
39 9434138 Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes. 1997 Nov 30 1
40 8667238 Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis). 1996 Jun 1
41 9018095 Dose-related increases in quantitative values for altered hepatocytic foci and cytochrome P-450 levels in the livers of rats exposed to phenobarbital in a medium-term bioassay. 1996 Dec 20 5
42 7477969 Cytochrome P450 and associated monooxygenase activities in the rat and human spinal cord: induction, immunological characterization and immunocytochemical localization. 1995 Sep 1
43 7616408 Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism. 1995 Jul 2
44 7628308 N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes. 1995 Mar 1
45 7728897 Characterization of hepatic microsomal cytochrome P-450 from rats treated with methylsulphonyl metabolites of polychlorinated biphenyl congeners. 1995 Apr 14 2
46 7732053 Circadian-time rhythm of hepatic protein kinase C of rats pretreated with phenobarbital. 1995 Mar 2
47 7759530 cAMP-associated inhibition of phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocyte cultures. 1995 May 26 3
48 8565792 Inhibition and induction of cytochrome P450 isozymes after repetitive administration of imipramine in rats. 1995 Sep 1
49 8031317 Cytochrome P450 destruction and radical scavenging by benzene and its metabolites. Evidence for the key role of quinones. 1994 Jun 15 2
50 8195225 Quantitative analyses of electrostatic interactions between NADPH-cytochrome P450 reductase and cytochrome P450 enzymes. 1994 Jun 3 1