Dicumarol

NAD(P)H dehydrogenase, quinone 1 ; Mus musculus







25 Article(s)
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1 32987030 Dicoumarol, an NQO1 inhibitor, blocks cccDNA transcription by promoting degradation of HBx. 2021 Mar 1
2 33460769 NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway. 2021 Feb 20 1
3 33228195 Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1). 2020 Nov 19 1
4 26612783 Can dicoumarol be used as a gonad-safe anticancer agent: an in vitro and in vivo experimental study. 2016 Jan 2
5 24598128 The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats. 2014 May 1
6 21296895 Genetic evidence for NAD(P)H:quinone oxidoreductase 1-catalyzed quinone reduction on passage through the mouse pulmonary circulation. 2011 May 1
7 21613233 Inhibition of renal NQO1 activity by dicoumarol suppresses nitroreduction of aristolochic acid I and attenuates its nephrotoxicity. 2011 Aug 2
8 18810995 Cytotoxicity of nitroaromatic explosives and their biodegradation products in mice splenocytes: implications for their immunotoxicity. 2008 Jul-Aug 1
9 16682409 Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis. 2006 Jul 21 1
10 15467770 Dietary induction of NQO1 increases the antitumour activity of mitomycin C in human colon tumours in vivo. 2004 Oct 18 1
11 12188909 Cancer therapy with beta-lapachone. 2002 Sep 3
12 10755406 A unique cytosolic activity related but distinct from NQO1 catalyses metabolic activation of mitomycin C. 2000 Apr 4
13 8763837 Induction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agents. 1996 Jul 1
14 7677784 Gene targeting of DT-diaphorase in mouse embryonic stem cells: establishment of null mutant and its mitomycin C-resistance. 1995 Sep 14 1
15 7690996 Menadione toxicity in two mouse liver established cell lines having striking genetic differences in quinone reductase activity and glutathione concentrations. 1993 Sep 1
16 1280990 Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells. 1992 Dec 1
17 1371987 Molecular mechanisms of trenimon-induced cytotoxicity in resistant L5178Y/HBM10 cells. 1992 1
18 1373799 Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia. 1992 Apr 1
19 1382426 Inhibition of mouse glutathione transferases and glutathione peroxidase II by dicumarol and other ligands. 1992 Sep 1 3
20 1692249 Activity of quinone alkylating agents in quinone-resistant cells. 1990 May 15 1
21 2471583 Increased sensitivity of quinone resistant cells to mitomycin C. 1989 Jun 1
22 2455523 DT-diaphorase activity and the cytotoxicity of quinones in C3H/10T1/2 mouse embryo cells. 1988 Jun 15 1
23 2419579 Use of quinones in brain-tumor therapy: preliminary results of preclinical laboratory investigations. 1985 1
24 3934922 Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C. 1985 1
25 6437671 Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1. 1984 Dec 1