Title : Sphingolipids as mediators of inflammation and novel therapeutic target in inflammatory bowel disease.

Pub. Date : 2020

PMID : 32085881






1 Functional Relationships(s)
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1 All GI tissues and circulating immune/blood cells contain activated sphingolipid-metabolizing enzymes, including sphingosine kinases (SphK1 and SphK2) that generate sphingosine-1-phosphate (S1P), a bioactive lipid and ligand for five G-protein coupled membrane S1P receptors (S1PRs). Sphingolipids sphingosine kinase 1 Homo sapiens