Title : Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.

Pub. Date : 2020 Jul 3

PMID : 32385114






1 Functional Relationships(s)
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1 Our results indicate that a SphK1 activator rescues aberrant cholesterol and sphingolipid storage and trafficking in NPC1 mutant cells. Sphingolipids sphingosine kinase 1 Homo sapiens