Epoxy Compounds

epoxide hydrolase 1 ; Homo sapiens







24 Article(s)
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1 34342583 EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. 2021 Aug 3 1
2 30644597 Emerging role of EPHX1 in chemoresistance of acute myeloid leukemia by regurlating drug-metabolizing enzymes and apoptotic signaling. 2019 May 1
3 29605894 EPHX1 rs1051740 T>C (Tyr113His) is strongly associated with acute myeloid leukemia and KMT2A rearrangements in early age. 2018 Jun 2
4 27256986 Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane. 2016 Aug 1
5 28071611 Microsomal epoxide hydrolase gene polymorphisms and susceptibility to prostate cancer: A systematic review. 2016 Apr-Jun 1
6 26216302 Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease. 2015 Oct 15 2
7 24309146 Discovery of soluble epoxide hydrolase inhibitors from natural products. 2014 Feb 1
8 23564882 Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5'-untranslated region. 2013 Jun 2
9 21983886 Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia. 2012 Mar 2
10 22118311 Polymorphism of microsomal epoxide hydrolase is associated with chronic obstructive pulmonary disease and bronchodilator response. 2011 Nov 2
11 19364907 The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. 2009 Jul 3
12 18614560 Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD. 2008 Oct 1
13 15716486 Variability in human sensitivity to 1,3-butadiene: influence of polymorphisms in the 5'-flanking region of the microsomal epoxide hydrolase gene (EPHX1). 2005 May 2
14 15826809 Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 A resolution: structure-activity relationships in epoxides inhibiting EH activity. 2005 Jun 1
15 15535985 Functional analysis of human microsomal epoxide hydrolase genetic variants. 2004 Nov 20 2
16 12605384 Variability in human sensitivity to 1,3-butadiene: Influence of the allelic variants of the microsomal epoxide hydrolase gene. 2003 1
17 11471167 Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking. 2001 Jul 22 2
18 11692079 Genetic polymorphisms of microsomal and soluble epoxide hydrolase and the risk of Parkinson's disease. 2001 Nov 1
19 11758809 Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours. 2001 Jun 1
20 10673439 Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases. 2000 Feb 15 1
21 10576413 Immunohistochemical detection of microsomal epoxide hydrolase in human synovial tissue. 1999 Oct 1
22 8819481 Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene. 1996 Sep 1
23 7769232 Localization of microsomal epoxide hydrolase in normal and neoplastic human kidney. 1995 Jun 1
24 6990840 [Microsomal epoxide hydrolase (author's transl)]. 1980 1