Anthracyclines

carbonyl reductase 1 ; Homo sapiens







17 Article(s)
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Pub. Year
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1 33581289 Carbonyl reduction pathway in hepatic in vitro metabolism of anthracyclines: Impact of structure on biotransformation rate. 2021 May 15 3
2 33774021 Association between the genetic polymorphisms of the pharmacokinetics of anthracycline drug and myelosuppression in a patient with breast cancer with anthracycline-based chemotherapy. 2021 Jul 1 1
3 32621953 The epigallocatechin gallate derivative Y6 reduces the cardiotoxicity and enhances the efficacy of daunorubicin against human hepatocellular carcinoma by inhibiting carbonyl reductase 1 expression. 2020 Oct 28 2
4 30611789 Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells - The involvement of carbonyl reductase 1 inhibition. 2019 Feb 25 2
5 26563179 Risk factors for anthracycline-associated cardiotoxicity. 2016 May 3
6 25541467 Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase--Carbonyl reductase 1. 2015 Jun 5 1
7 25549925 Structure-activity relationship of flavonoids as potent inhibitors of carbonyl reductase 1 (CBR1). 2015 Mar 2
8 26068795 Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1. 2015 Jul 21 3
9 26415702 The modulation of carbonyl reductase 1 by polyphenols. 2015 2
10 23247010 Regulation of human carbonyl reductase 1 (CBR1, SDR21C1) gene by transcription factor Nrf2. 2013 Feb 25 3
11 20670211 Daunorubicin metabolism in leukemic cells isolated from patients with acute myeloid leukemia. 2010 Dec 2
12 20729274 Expression of the anthracycline-metabolizing enzyme carbonyl reductase 1 in hearts from donors with Down syndrome. 2010 Dec 4
13 19022938 Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors. 2009 Feb 1
14 19204081 Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin. 2009 May 1
15 18449627 Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER). 2008 Jul 1
16 17344335 A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. 2007 Jun 2
17 15799708 An unbiased cell morphology-based screen for new, biologically active small molecules. 2005 May 1