Title : A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity.

Pub. Date : 2007 Jun

PMID : 17344335






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Human carbonyl reductase 1 (CBR1) metabolizes endogenous and xenobiotic substrates such as the fever mediator, prostaglandin E2 (PGE2), and the anticancer anthracycline drug, daunorubicin. Anthracyclines carbonyl reductase 1 Homo sapiens
2 Human carbonyl reductase 1 (CBR1) metabolizes endogenous and xenobiotic substrates such as the fever mediator, prostaglandin E2 (PGE2), and the anticancer anthracycline drug, daunorubicin. Anthracyclines carbonyl reductase 1 Homo sapiens