| 1 |
33517269 | Urokinase-type Plasminogen Activator Is a Therapeutic Target for Overcoming Sorafenib Resistance in Hepatoma Cells. | 2021 Feb |
1 |
| 2 |
33804289 | Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors. | 2021 Mar 15 |
2 |
| 3 |
29328476 | Effect of a synthetic inhibitor of urokinase plasminogen activator on the migration and invasion of human cervical cancer cells in vitro. | 2018 Mar |
8 |
| 4 |
25972510 | Aberrant glomerular filtration of urokinase-type plasminogen activator in nephrotic syndrome leads to amiloride-sensitive plasminogen activation in urine. | 2015 Aug 1 |
6 |
| 5 |
24885350 | Identification of genes regulating migration and invasion using a new model of metastatic prostate cancer. | 2014 May 30 |
1 |
| 6 |
25492830 | Amiloride lowers blood pressure and attenuates urine plasminogen activation in patients with treatment-resistant hypertension. | 2014 Dec |
2 |
| 7 |
24023701 | Involvement of the serine protease inhibitor, SERPINE2, and the urokinase plasminogen activator in cumulus expansion and oocyte maturation. | 2013 |
1 |
| 8 |
22366654 | 2-Amidino analogs of glycine-amiloride conjugates: inhibitors of urokinase-type plasminogen activator. | 2012 Apr 1 |
2 |
| 9 |
23234499 | u-PA inhibitor amiloride suppresses peritoneal metastasis in gastric cancer. | 2012 Dec 12 |
3 |
| 10 |
21470685 | Participation of the urokinase-type plasminogen activator receptor (uPAR) in neutrophil transendothelial migration. | 2011 May |
2 |
| 11 |
21978672 | Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA). | 2011 Nov 15 |
8 |
| 12 |
20180817 | Enhanced cell-associated plasminogen activator pathway but not coagulation pathway activity contributes to motility in metastatic breast cancer cells. | 2010 Jun |
1 |
| 13 |
19436306 | Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system. | 2009 May 19 |
3 |
| 14 |
18366077 | Plasminogen-induced aggregation of PANC-1 cells requires conversion to plasmin and is inhibited by endogenous plasminogen activator inhibitor-1. | 2008 Sep |
1 |
| 15 |
17210677 | Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion. | 2007 Jan 1 |
1 |
| 16 |
16611636 | Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation. | 2006 Jun 9 |
1 |
| 17 |
16636720 | Topical amiloride ointment accelerates healing of mechanical skin ulcers in albino rabbits and patients. | 2006 Mar |
1 |
| 18 |
14973065 | Tumor necrosis factor-alpha-induced matrix proteolytic enzyme production and basement membrane remodeling by human ovarian surface epithelial cells: molecular basis linking ovulation and cancer risk. | 2004 Feb 15 |
3 |
| 19 |
15023541 | Extracellular alpha 6 integrin cleavage by urokinase-type plasminogen activator in human prostate cancer. | 2004 Apr 1 |
1 |
| 20 |
15543335 | Neutrophils stimulated by apolipoprotein(a) generate fragments that are stronger inhibitors of plasmin formation than apo(a). | 2004 Nov |
1 |
| 21 |
14644129 | Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion. | 2003 Dec |
1 |
| 22 |
11835393 | Association between alphavbeta6 integrin expression, elevated p42/44 kDa MAPK, and plasminogen-dependent matrix degradation in ovarian cancer. | 2002 |
1 |
| 23 |
11991662 | Receptor-bound uPA is reversibly protected from inhibition by low molecular weight inhibitors. | 2002 |
5 |
| 24 |
11454671 | Amplification of urokinase gene in prostate cancer. | 2001 Jul 15 |
1 |
| 25 |
11562773 | Binding site of amiloride to urokinase plasminogen activator depends on species. | 2001 Oct |
1 |
| 26 |
11758807 | IL-1beta increases uPA and uPA receptor expression in human gingival fibroblasts. | 2001 Jun |
1 |
| 27 |
11804183 | Osteopontin(OPN)-induced increase in human mammary epithelial cell invasiveness is urokinase (uPA)-dependent. | 2001 Dec |
2 |
| 28 |
10824746 | Suppression of the invasive capacity of human breast cancer cells by inhibition of urokinase plasminogen activator via amiloride and B428. | 2000 May |
2 |
| 29 |
10328652 | Increase of urokinase-type plasminogen activator receptor expression in human gingival fibroblasts by Porphyromonas gingivalis lipopolysaccharide. | 1999 Apr |
1 |
| 30 |
10738907 | Molecular basis of specific inhibition of urokinase plasminogen activator by amiloride. | 1999 Jul |
3 |
| 31 |
9665481 | Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met. | 1998 Jul |
1 |
| 32 |
8627323 | Modulation of serine proteinases and metalloproteinases during morphogenic glial-endothelial interactions. | 1996 Apr |
2 |
| 33 |
7750207 | Amiloride modulates urokinase gene expression at both transcription and post-transcription levels in human colon cancer cells. | 1995 May |
3 |
| 34 |
8495419 | Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitor. | 1993 Jun 1 |
1 |
| 35 |
1915841 | Characterization of a tissue-type plasminogen activator from porcine urine. | 1991 Sep 9 |
1 |
| 36 |
3106085 | Amiloride selectively inhibits the urokinase-type plasminogen activator. | 1987 Apr 6 |
7 |