Choline

choline kinase alpha ; Homo sapiens







38 Article(s)
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Pub. Year
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1 34985768 Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cells. 2022 May 1 4
2 35159102 ATP8B1 Knockdown Activated the Choline Metabolism Pathway and Induced High-Level Intracellular REDOX Homeostasis in Lung Squamous Cell Carcinoma. 2022 Feb 7 1
3 33390181 Choline kinase alpha impairment overcomes TRAIL resistance in ovarian cancer cells. 2021 Jan 4 2
4 34202989 ChoK-Full of Potential: Choline Kinase in B Cell and T Cell Malignancies. 2021 Jun 20 1
5 34452207 Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics. 2021 Aug 12 1
6 31745227 Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase. 2019 Nov 19 1
7 31788037 A rapid and adaptable lipidomics method for quantitative UPLC-mass spectrometric analysis of phosphatidylethanolamine and phosphatidylcholine in vitro, and in cells. 2019 Apr 7 1
8 31817833 Imaging and Tissue Biomarkers of Choline Metabolism in Diffuse Adult Glioma: 18F-Fluoromethylcholine PET/CT, Magnetic Resonance Spectroscopy, and Choline Kinase α. 2019 Dec 7 1
9 28065789 Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression. 2017 Apr 2
10 28509322 Polymorphic variants of genes involved in choline pathway and the risk of intrauterine fetal death. 2017 2
11 28654865 Molecular Effects of Doxorubicin on Choline Metabolism in Breast Cancer. 2017 Aug 2
12 29138500 Circulating androgen receptor combined with 18F-fluorocholine PET/CT metabolic activity and outcome to androgen receptor signalling-directed therapies in castration-resistant prostate cancer. 2017 Nov 14 1
13 27588131 CHKA mediates the poor prognosis of lung adenocarcinoma and acts as a prognostic indicator. 2016 Sep 2
14 27705917 Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. 2016 Nov 8 2
15 27747192 Key Players in Choline Metabolic Reprograming in Triple-Negative Breast Cancer. 2016 1
16 25333818 Expression profiling of choline and ethanolamine kinases in MCF7, HCT116 and HepG2 cells, and the transcriptional regulation by epigenetic modification. 2015 Jan 1
17 25487918 Preclinical characterization of RSM-932A, a novel anticancer drug targeting the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells. 2015 Jan 2
18 25768400 Dysregulated choline metabolism in T-cell lymphoma: role of choline kinase-α and therapeutic targeting. 2015 Mar 13 2
19 25921026 Choline metabolism-based molecular diagnosis of cancer: an update. 2015 Jun 1
20 26041862 Exploiting altered patterns of choline kinase-alpha expression on human prostate tissue to prognosticate prostate cancer. 2015 Sep 1
21 26503172 Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival. 2015 Dec 2
22 24281000 Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer. 2014 Jan 21 1
23 24440820 Choline kinase alpha expression during RA-induced neuronal differentiation: role of C/EBPβ. 2014 Apr 4 2
24 24447408 Interplay of choline metabolites and genes in patient-derived breast cancer xenografts. 2014 Jan 21 4
25 24556997 Phospholipase D1 and choline kinase-α are interactive targets in breast cancer. 2014 May 3
26 24671709 Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups. 2014 Jul 1
27 25267063 Alterations of choline phospholipid metabolism in endometrial cancer are caused by choline kinase alpha overexpression and a hyperactivated deacylation pathway. 2014 Dec 1 1
28 22025560 Choline phosphorylation and regulation of transcription of choline kinase α in hypoxia. 2012 Jan 1
29 22279038 Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer. 2012 Sep 2
30 21862943 Biological basis of [¹¹C]choline-positron emission tomography in patients with breast cancer: comparison with [¹⁸F]fluorothymidine positron emission tomography. 2011 Nov 2
31 19336572 Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft. 2009 Apr 15 1
32 18029352 Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis. 2008 Jan 18 1
33 18056454 Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells. 2007 Dec 1 2
34 16371353 A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis. 2006 Feb 24 1
35 20641747 [11C]Choline 2004 2
36 20641761 [18F]Fluorocholine 2004 2
37 21735582 [18F]Fluoro-[1,2-2H4]choline 2004 3
38 21735583 [18F]Fluoroethylcholine 2004 3