Sirolimus

CD4 antigen ; Mus musculus







29 Article(s)
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1 33887578 Immunotherapeutic strategy based on anti-OX40L and low dose of IL-2 to prolong graft survival in sensitized mice by inducing the generation of CD4+ and CD8+ Tregs. 2021 Aug 1
2 34015361 Rapamycin delays allograft rejection in obese graft recipients through induction of myeloid-derived suppressor cells. 2021 Aug 1
3 34912349 Impact of Graft-Resident Leucocytes on Treg Mediated Skin Graft Survival. 2021 1
4 33255287 Rapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. 2020 Nov 24 2
5 30654047 Early-life undernutrition reprograms CD4+ T-cell glycolysis and epigenetics to facilitate asthma. 2019 Jun 1
6 31004709 Rapamycin relieves inflammation of experimental autoimmune encephalomyelitis by altering the balance of Treg/Th17 in a mouse model. 2019 Jul 13 1
7 29562463 [Rapamycin affect the apoptosis of splenic CD4+CD25+ regulatory T cells of mouse severe aplastic anemia model]. 2018 Mar 14 2
8 29732501 PKM2-dependent metabolic reprogramming in CD4+ T cells is crucial for hyperhomocysteinemia-accelerated atherosclerosis. 2018 Jun 1
9 27974559 mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses. 2017 Feb 15 1
10 25867817 iPSC-MSCs Combined with Low-Dose Rapamycin Induced Islet Allograft Tolerance Through Suppressing Th1 and Enhancing Regulatory T-Cell Differentiation. 2015 Aug 1 1
11 26782505 Influence of sirolimus-induced TGF-β secretion on mouse Treg cell proliferation. 2015 Dec 28 4
12 22769982 Pretreatment of rapamycin before allogenic corneal transplant promotes graft survival through increasing CD4(+)CD25(+)Foxp3(+) regulatory T cells. 2013 Feb 2
13 23349887 Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma. 2013 1
14 23480027 Sirolimus ameliorates inflammatory responses by switching the regulatory T/T helper type 17 profile in murine colitis. 2013 Aug 5
15 23991087 Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity. 2013 2
16 24078700 Increased mammalian target of rapamycin complex 2 signaling promotes age-related decline in CD4 T cell signaling and function. 2013 Nov 1 1
17 24090996 Distinct sensitivity of CD8+ CD4- and CD8+ CD4+ leukemic cell subpopulations to cyclophosphamide and rapamycin in Notch1-induced T-ALL mouse model. 2013 Nov 2
18 24265670 Beneficial role of rapamycin in experimental autoimmune myositis. 2013 1
19 22189601 Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model. 2012 Apr 3
20 20149931 Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation. 2010 Mar 30 1
21 19539558 Combined therapy of CD4(+)CD25(+) regulatory T cells with low-dose sirolimus, but not calcineurin inhibitors, preserves suppressive function of regulatory T cells and prolongs allograft survival in mice. 2009 May 3
22 17331841 The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice. 2007 Apr 4
23 17351648 Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells. 2007 May 3
24 17142730 Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. 2006 Dec 15 1
25 15746082 Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. 2005 Jun 15 1
26 15210777 Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection. 2004 Jul 1 1
27 9566798 The effect of cyclosporin A, FK506 and rapamycin on the murine contact sensitivity reaction. 1998 Apr 1
28 7540861 Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin. 1995 Mar 1
29 8228258 Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration of rapamycin but develop an autoimmune-like syndrome. 1993 Nov 15 3