Pub. Date : 2007 May
PMID : 17351648
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells. | Sirolimus | CD4 antigen | Mus musculus | ||
| 2 | Prolonged rapamycin treatment allowed for thymic generation of CD4(+)FoxP3(+) T cells, whereas treatment with cyclosporine led to a reduced generation of these cells. | Sirolimus | CD4 antigen | Mus musculus | ||
| 3 | In conclusion, cyclosporine and rapamycin differentially affect homeostasis of CD4(+)FoxP3(+) T(REG) in vivo. | Sirolimus | CD4 antigen | Mus musculus | ||