| 1 |
35449859 | Dexmedetomidine Attenuates LPS-Induced Acute Lung Injury in Rats by Activating the Nrf2/ARE Pathway. | 2022 |
1 |
| 2 |
35486975 | Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway. | 2022 Jun |
1 |
| 3 |
35488217 | Dexmedetomidine attenuates oxygen-glucose deprivation/ reperfusion-induced inflammation through the miR-17-5p/ TLR4/ NF-κB axis. | 2022 Apr 29 |
2 |
| 4 |
33076786 | Dexmedetomidine improves postoperative neurocognitive disorder after cardiopulmonary bypass in rats. | 2021 Feb |
1 |
| 5 |
33280824 | The Protective Effects of Dexmedetomidine Preconditioning on Hepatic Ischemia/Reperfusion Injury in Rats. | 2021 Jan-Feb |
1 |
| 6 |
33499703 | Dexmedetomidine postconditioning alleviates spinal cord ischemia-reperfusion injury in rats via inhibiting neutrophil infiltration, microglia activation, reactive gliosis and CXCL13/CXCR5 axis activation. | 2021 Mar 11 |
1 |
| 7 |
33770644 | Alpha and beta adrenoceptors activate interleukin-6 transcription through different pathways in cultured astrocytes from rat spinal cord. | 2021 Jun |
1 |
| 8 |
34363182 | Dexmedetomidine Alleviates Lipopolysaccharide-Induced Hippocampal Neuronal Apoptosis via Inhibiting the p38 MAPK/c-Myc/CLIC4 Signaling Pathway in Rats. | 2021 Nov |
1 |
| 9 |
34622713 | Effects of dexmedetomidine on postoperative cognitive function of sleep deprivation rats based on changes in inflammatory response. | 2021 Dec |
1 |
| 10 |
34848804 | Comparative effects of dexmedetomidine and propofol on brain and lung damage in experimental acute ischemic stroke. | 2021 Nov 30 |
1 |
| 11 |
31834821 | Dexmedetomidine Exerts Brain-Protective Effects Under Cardiopulmonary Bypass Through Inhibiting the Janus Kinase 2/Signal Transducers and Activators of Transcription 3 Pathway. | 2020 Feb |
1 |
| 12 |
32014689 | Effects of dexmedetomidine on lipopolysaccharide-induced acute kidney injury in rats and mitochondrial function in cell culture. | 2020 May |
1 |
| 13 |
32163856 | Dexmedetomidine inhibits the invasion, migration, and inflammation of rheumatoid arthritis fibroblast-like synoviocytes by reducing the expression of NLRC5. | 2020 Mar 9 |
2 |
| 14 |
32317860 | Dexmedetomidine Protects against Ischemia and Reperfusion-Induced Kidney Injury in Rats. | 2020 |
2 |
| 15 |
32415933 | Effects of dexmedetomidine pretreatment on rats with sepsis-induced acute kidney injury and miR-146a expression. | 2020 May 15 |
1 |
| 16 |
32706450 | Analgesic effect of dexmedetomidine in rats after chronic constriction injury by mediating microRNA-101 expression and the E2F2-TLR4-NF-κB axis. | 2020 Sep |
1 |
| 17 |
32742334 | Dexmedetomidine-mediated regulation of miR-17-3p in H9C2 cells after hypoxia/reoxygenation injury. | 2020 Aug |
1 |
| 18 |
33275257 | Protective effect of dexmedetomidine against renal injury in diabetic nephropathy rats through inhibiting NF-κB pathway. | 2020 Nov |
2 |
| 19 |
33287729 | Perioperative Dexmedetomidine attenuates brain ischemia reperfusion injury possibly via up-regulation of astrocyte Connexin 43. | 2020 Dec 7 |
1 |
| 20 |
29683965 | Effect of Dexmedetomidine on Cerebral Vasospasm and Associated Biomarkers in a Rat Subarachnoid Hemorrhage Model. | 2019 Jul |
3 |
| 21 |
30657579 | Dexmedetomidine alleviates lung ischemia-reperfusion injury in rats by activating PI3K/Akt pathway. | 2019 Jan |
1 |
| 22 |
31344138 | Dexmedetomidine-induced cardioprotection is mediated by inhibition of high mobility group box-1 and the cholinergic anti-inflammatory pathway in myocardial ischemia-reperfusion injury. | 2019 |
1 |
| 23 |
31476326 | Dexmedetomidine attenuates the induction and reverses the progress of 6-hydroxydopamine- induced parkinsonism; involvement of KATP channels, alpha 2 adrenoceptors and anti-inflammatory mechanisms. | 2019 Nov 1 |
1 |
| 24 |
31478596 | Dexmedetomidine Attenuates Neuroinflammatory-Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway. | 2019 Sep |
1 |
| 25 |
31589938 | Dexmedetomidine Attenuates Lung Injury in Obstructive Jaundice Rats Through PI3K/Akt/HIF-1α Signaling Pathway. | 2019 Jul |
1 |
| 26 |
31623841 | Dexmedetomidine modulates neuroinflammation and improves outcome via alpha2-adrenergic receptor signaling after rat spinal cord injury. | 2019 Dec |
1 |
| 27 |
29241031 | The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways. | 2018 Feb |
1 |
| 28 |
29723264 | Dexmedetomidine inhibits inflammatory reaction in the hippocampus of septic rats by suppressing NF-κB pathway. | 2018 |
2 |
| 29 |
30017939 | Comparison of neurotoxicity of dexmedetomidine as an adjuvant in brachial plexus block in rats of different age. | 2018 Sep - Oct |
1 |
| 30 |
30259406 | Dexmedetomidine Relieves Acute Inflammatory Visceral Pain in Rats through the ERK Pathway, Toll-Like Receptor Signaling, and TRPV1 Channel. | 2018 Oct |
1 |
| 31 |
30377100 | [Dexmedetomidine alleviates postoperative cognitive dysfunction in aged rats probably via silent information regulator 1 pathway]. | 2018 Aug 30 |
1 |
| 32 |
27998004 | Dexmedetomidine preconditioning for myocardial protection in ischaemia-reperfusion injury in rats by downregulation of the high mobility group box 1-toll-like receptor 4-nuclear factor κB signalling pathway. | 2017 Mar |
1 |
| 33 |
28222157 | Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway. | 2017 |
1 |
| 34 |
29033541 | Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2-STAT3 pathway. | 2017 |
1 |
| 35 |
29359143 | Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling. | 2017 |
1 |
| 36 |
26655164 | Neuroprotective effects of dexmedetomidine conditioning strategies: Evidences from an in vitro model of cerebral ischemia. | 2016 Jan 1 |
1 |
| 37 |
26896779 | Effect of dexmedetomidine and cold stress in a rat model of neuropathic pain: Role of interleukin-6 and tumor necrosis factor-α. | 2016 Apr 5 |
2 |
| 38 |
27480658 | [The protective effect of alpha-2 adrenergic agonist on cranial nerve in rats with brain injury]. | 2016 Jul 26 |
1 |
| 39 |
25929655 | The effect of dexmedetomidine on inflammatory response of septic rats. | 2015 May 1 |
1 |
| 40 |
26181644 | Preclinical efficacy of Dexmedetomidine on spinal cord injury provoked oxidative renal damage. | 2015 Aug |
1 |
| 41 |
26273145 | Dexmedetomidine Ameliorate CLP-Induced Rat Intestinal Injury via Inhibition of Inflammation. | 2015 |
1 |
| 42 |
26628956 | Dexmedetomidine alleviates the spinal cord ischemia-reperfusion injury through blocking mast cell degranulation. | 2015 |
1 |
| 43 |
24345905 | Effect of dexmedetomidine on lung ischemia‑reperfusion injury. | 2014 Feb |
1 |
| 44 |
24663080 | Perineural dexmedetomidine attenuates inflammation in rat sciatic nerve via the NF-κB pathway. | 2014 Mar 6 |
1 |
| 45 |
25069417 | Dexmedetomidine suppresses interleukin-1β-induced interleukin-6 synthesis in rat glial cells. | 2014 Oct |
5 |
| 46 |
23690665 | Dexmedetomidine inhibits inflammatory reaction in lung tissues of septic rats by suppressing TLR4/NF-κB pathway. | 2013 |
1 |
| 47 |
19519725 | Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury. | 2009 Sep |
1 |
| 48 |
19608326 | Dexmedetomidine-ketamine combination mitigates acute lung injury in haemorrhagic shock rats. | 2009 Oct |
1 |
| 49 |
19691839 | Sedation improves early outcome in severely septic Sprague Dawley rats. | 2009 |
2 |
| 50 |
15187514 | Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats. | 2004 Jun |
1 |