Title : Dexmedetomidine Alleviates Lipopolysaccharide-Induced Hippocampal Neuronal Apoptosis via Inhibiting the p38 MAPK/c-Myc/CLIC4 Signaling Pathway in Rats.

Pub. Date : 2021 Nov

PMID : 34363182






1 Functional Relationships(s)
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1 DEX also attenuated LPS-induced inflammation and hippocampal apoptosis by inhibiting the increase of interleukin-1beta, interleukin-6, interleukin-18, and tumor necrosis factor-alpha levels and downregulating the expression of mitochondrial apoptosis pathway-related proteins. Dexmedetomidine interleukin 6 Rattus norvegicus