Pub. Date : 2014 Oct
PMID : 25069417
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexmedetomidine suppresses interleukin-1beta-induced interleukin-6 synthesis in rat glial cells. | Dexmedetomidine | interleukin 6 | Rattus norvegicus |
| 2 | In the present study, we investigated the effects of dexmedetomidine on the IL-1beta-induced IL-6 synthesis in C6 cells. | Dexmedetomidine | interleukin 6 | Rattus norvegicus |
| 3 | Dexmedetomidine inhibited the IL-1beta-stimulated IL-6 release and mRNA expression in C6 cells. | Dexmedetomidine | interleukin 6 | Rattus norvegicus |
| 4 | Our findings strongly suggest that dexmedetomidine inhibits the IL-1beta-induced IL-6 synthesis independently of the adenylyl cyclase-cAMP pathway through alpha2-adrenoceptors in C6 glioma cells. | Dexmedetomidine | interleukin 6 | Rattus norvegicus |
| 5 | It is possible that dexmedetomidine may affect the immune system in the CNS by regulating the production of IL-6. | Dexmedetomidine | interleukin 6 | Rattus norvegicus |