Methylcholanthrene

cytochrome P450, family 1, subfamily a, polypeptide 2 ; Mus musculus







15 Article(s)
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Pub. Year
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1 30503582 Strain differences between CD-1 and C57BL/6 mice in expression of metabolic enzymes and DNA methylation modifications of the primary hepatocytes. 2019 Jan 15 1
2 23169610 The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene. 2013 Feb 1
3 24362577 Chimeric mice with humanized livers: a unique tool for in vivo and in vitro enzyme induction studies. 2013 Dec 20 1
4 20595379 Regulatory xenobiotic responsive elements in the distal 5'-flanking region of the mouse Cyp1a2 gene required for transcriptional activation by 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2010 Oct 3
5 20732958 Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo. 2010 Nov 6
6 18956144 Absolute requirement for iron in the development of chemically induced uroporphyria in mice treated with 3-methylcholanthrene and 5-aminolevulinate. 2009 Apr 2
7 19772856 Hyper- and hypo-induction of cytochrome P450 activities with Aroclor 1254 and 3-methylcholanthrene in Cyp1a2(-/-) mice. 2009 Dec 10 3
8 19900403 Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters. 2009 Dec 25 1
9 12438513 Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene. 2002 Dec 5
10 10820145 Use of a novel real-time quantitative reverse transcription-polymerase chain reaction method to study the effects of cytokines on cytochrome P450 mRNA expression in mouse liver. 2000 Jun 1
11 10424773 Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization. 1999 Aug 1 3
12 9461503 Uroporphyria produced in mice by iron and 5-aminolaevulinic acid does not occur in Cyp1a2(-/-) null mutant mice. 1998 Feb 15 4
13 9128719 Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene. 1997 Apr 1 3
14 8886157 Detection and localization of CYP1A1/CYP1A2 in murine liver: electrophoresis, immunoblotting and immunocytochemistry. 1995 Dec 1
15 8486528 Activation of Cyp1a1 and Cyp1a2 genes in adult mouse hepatocytes in primary culture. 1993 Mar 1