Title : PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration.

Pub. Date : 2003 Jan 6

PMID : 12515828






3 Functional Relationships(s)
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1 Reintroduction of active (but not inactive) PTP alpha restored FAK Tyr-397 phosphorylation. Tyrosine PTK2 protein tyrosine kinase 2 Mus musculus
2 Our paper establishes that PTP alpha is required for early integrin-proximal events, acting upstream of FAK to affect the timely and efficient phosphorylation of FAK Tyr-397. Tyrosine PTK2 protein tyrosine kinase 2 Mus musculus
3 Our paper establishes that PTP alpha is required for early integrin-proximal events, acting upstream of FAK to affect the timely and efficient phosphorylation of FAK Tyr-397. Tyrosine PTK2 protein tyrosine kinase 2 Mus musculus