Metyrapone

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







12 Article(s)
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1 30676743 Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules. 2019 Feb 19 3
2 22113809 Binding free energies of inhibitors to iron porphyrin complex as a model for Cytochrome P450. 2012 Apr 1
3 19727863 Probing possible egress channels for multiple ligands in human CYP3A4: a molecular modeling study. 2010 Apr 1
4 19414330 Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. 2009 Mar 2
5 17520814 [Characteristics of uptake, transport and efflux of Z- and E-ajoenes in Caco-2 cell monolayers in vitro]. 2007 Jan 1
6 16713641 Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. 2006 Jun 30 1
7 16190729 Structural and dynamical basis of broad substrate specificity, catalytic mechanism, and inhibition of cytochrome P450 3A4. 2005 Oct 5 1
8 15100175 Role of Sp1, C/EBP alpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene. 2004 May 1
9 15256616 Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. 2004 Jul 30 2
10 10611146 Effect of the adrenal 11-beta-hydroxylase inhibitor metyrapone on human hepatic cytochrome P-450 expression: induction of cytochrome P-450 3A4. 2000 Jan 6
11 10219967 A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. 1999 Mar 1
12 10917608 The cytochrome P450 3A4 inducer metyrapone is an activator of the human pregnane X receptor. 1999 Aug 1