UK 453,061

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







5 Article(s)
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Title
Pub. Year
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1 22040521 Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects. 2012 May 1
2 22123705 Pharmacokinetic effects of coadministration of lersivirine with raltegravir or maraviroc in healthy subjects. 2012 Feb 4
3 22644026 Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-O-desacetyl-rifabutin in healthy subjects. 2012 Aug 3
4 22682979 Effect of lersivirine co-administration on pharmacokinetics of methadone in healthy volunteers. 2012 Nov 1 3
5 20124396 Excretion and metabolism of lersivirine (5-{[3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a next-generation non-nucleoside reverse transcriptase inhibitor, after administration of [14C]Lersivirine to healthy volunteers. 2010 May 1