Title : Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.

Pub. Date : 2012 May

PMID : 22040521






1 Functional Relationships(s)
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1 CONCLUSIONS: Inhibition of CYP3A4 and UGT2B7 by ketoconazole increased lersivirine exposure. UK 453,061 cytochrome P450 family 3 subfamily A member 4 Homo sapiens