| 1 |
33790108 | Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies. | 2021 |
5 |
| 2 |
28278026 | 7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites. | 2018 Mar |
1 |
| 3 |
23434495 | Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry. | 2013 Apr 15 |
1 |
| 4 |
23651100 | Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone. | 2013 Jul 15 |
3 |
| 5 |
21177853 | Analysis of heterotropic cooperativity in cytochrome P450 3A4 using alpha-naphthoflavone and testosterone. | 2011 Feb 18 |
5 |
| 6 |
22004098 | Allosteric activation of cytochrome P450 3A4 by α-naphthoflavone: branch point regulation revealed by isotope dilution analysis. | 2011 Nov 22 |
1 |
| 7 |
19299527 | Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. | 2009 Jun |
1 |
| 8 |
21218106 | Experimental approaches to evaluate activities of cytochromes P450 3A. | 2008 Sep |
1 |
| 9 |
17198380 | Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe. | 2007 Jan 9 |
1 |
| 10 |
17459328 | Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4. | 2007 Jul 1 |
3 |
| 11 |
17573349 | Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes. | 2007 Sep 28 |
2 |
| 12 |
15546903 | CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis. | 2005 Feb |
2 |
| 13 |
15870379 | Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneity. | 2005 Aug |
4 |
| 14 |
15005856 | CYP3A4 is a human microsomal vitamin D 25-hydroxylase. | 2004 Apr |
2 |
| 15 |
12893521 | In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes. | 2003 Jul |
1 |
| 16 |
12067248 | 7-Benzyloxyquinoline oxidation by P450eryF A245T: finding of a new fluorescent substrate probe. | 2002 Jun |
2 |
| 17 |
11054425 | A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4. | 2001 Jan 19 |
2 |
| 18 |
10821163 | Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450. | 2000 Apr |
1 |
| 19 |
10385214 | Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5. | 1999 Apr |
1 |
| 20 |
10548449 | Activation of phenacetin O-deethylase activity by alpha-naphthoflavone in human liver microsomes. | 1999 Sep |
3 |
| 21 |
9473295 | Analysis of four residues within substrate recognition site 4 of human cytochrome P450 3A4: role in steroid hydroxylase activity and alpha-naphthoflavone stimulation. | 1998 Feb 15 |
1 |
| 22 |
9521735 | Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites. | 1998 Mar 24 |
1 |
| 23 |
9825830 | In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol. | 1998 Oct |
1 |
| 24 |
10022752 | Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone. | 1998 Apr |
4 |
| 25 |
9202751 | The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies. | 1997 May 12 |
1 |
| 26 |
9220969 | Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis. | 1997 Jul 22 |
1 |
| 27 |
9223567 | Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites. | 1997 Jul |
1 |
| 28 |
9431830 | Characterization of the human cytochrome P450 enzymes involved in the metabolism of dihydrocodeine. | 1997 Dec |
1 |
| 29 |
8886602 | Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450. | 1996 Sep |
1 |
| 30 |
7883227 | Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues. | 1995 Feb |
1 |
| 31 |
7833826 | Modulation of cytochrome P450 activities by 7,8-benzoflavone and its metabolites. | 1994 Oct |
1 |
| 32 |
8010982 | Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation. | 1994 Jun 1 |
4 |
| 33 |
8054246 | In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase. | 1994 May |
1 |
| 34 |
8204577 | Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site. | 1994 May 31 |
3 |