Title : Experimental approaches to evaluate activities of cytochromes P450 3A.

Pub. Date : 2008 Sep

PMID : 21218106






1 Functional Relationships(s)
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1 The aim of this study was to evaluate the efficiency of different in vitro systems containing individual enzymes of the mixed-function monooxygenase system to oxidize two model substrates of CYP3A enzymes, exogenous and endogenous compounds, alpha-naphtoflavone (alpha-NF) and testosterone, respectively. alpha-naphthoflavone cytochrome P450 family 3 subfamily A member 4 Homo sapiens