| 1 |
35022331 | TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer. | 2022 Jan 12 |
5 |
| 2 |
35207462 | Down-Regulation of C1GALT1 Enhances the Progression of Cholangiocarcinoma through Activation of AKT/ERK Signaling Pathways. | 2022 Jan 25 |
1 |
| 3 |
34588619 | Epigenetic induction of lipocalin 2 expression drives acquired resistance to 5-fluorouracil in colorectal cancer through integrin β3/SRC pathway. | 2021 Nov |
1 |
| 4 |
34596215 | Syndecan-2, negatively regulated by miR-20b-5p, contributes to 5-fluorouracil resistance of colorectal cancer cells via the JNK/ERK signaling pathway. | 2021 Nov 10 |
5 |
| 5 |
34605226 | A Novel Mechanism of Endoplasmic Reticulum Stress- and c-Myc-Degradation-Mediated Therapeutic Benefits of Antineurokinin-1 Receptor Drugs in Colorectal Cancer. | 2021 Nov |
1 |
| 6 |
32606741 | β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways. | 2020 |
4 |
| 7 |
30579838 | Schedule-dependent synergistic effects of 5-fluorouracil and selumetinib in KRAS or BRAF mutant colon cancer models. | 2019 Feb |
1 |
| 8 |
30770552 | Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5-fluorouracil against human hepatocellular carcinoma. | 2019 Feb 15 |
1 |
| 9 |
30993729 | Aluminum chloride causes 5-fluorouracil resistance in hepatocellular carcinoma HepG2 cells. | 2019 Nov |
1 |
| 10 |
28226315 | The Novel Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) Alone and in Dual-Targeting Approaches Demonstrates Antitumoral Efficacy in Neuroendocrine Tumors in vitro. | 2018 |
1 |
| 11 |
29560281 | Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma. | 2018 |
1 |
| 12 |
29777330 | Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer. | 2018 Jun |
1 |
| 13 |
29917268 | KAP1 inhibits the Raf-MEK-ERK pathway to promote tumorigenesis in A549 lung cancer cells. | 2018 Oct |
1 |
| 14 |
30011079 | Effect of 5-fluorouracil on excision repair cross-complementing 1 expression and consequent cytotoxicity regulation in human gastric cancer cells. | 2018 Nov |
1 |
| 15 |
28058860 | Liposome-mediated RNA interference delivery against Erk1 and Erk2 does not equally promote chemosensitivity in human hepatocellular carcinoma cell line HepG2. | 2017 Dec |
3 |
| 16 |
28759561 | Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway. | 2017 Jul 31 |
1 |
| 17 |
26494468 | DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53. | 2016 Apr |
1 |
| 18 |
26687645 | Oxymatrine synergistically enhances the inhibitory effect of 5-fluorouracil on hepatocellular carcinoma in vitro and in vivo. | 2016 Jun |
1 |
| 19 |
27163731 | Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cells. | 2016 Jun |
1 |
| 20 |
27942222 | CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer. | 2016 |
2 |
| 21 |
25333998 | Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells. | 2015 Jan |
1 |
| 22 |
25714249 | Chlorogenic acid enhances the effects of 5-fluorouracil in human hepatocellular carcinoma cells through the inhibition of extracellular signal-regulated kinases. | 2015 Jun |
1 |
| 23 |
25826088 | Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. | 2015 Apr 20 |
1 |
| 24 |
26151540 | MicroRNA‑197 reverses the drug resistance of fluorouracil‑induced SGC7901 cells by targeting mitogen‑activated protein kinase 1. | 2015 Oct |
2 |
| 25 |
26316041 | E-cadherin knockdown increases β-catenin reducing colorectal cancer chemosensitivity only in three-dimensional cultures. | 2015 Oct |
1 |
| 26 |
24788596 | Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. | 2014 Jun |
1 |
| 27 |
23837948 | Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway. | 2013 Dec |
3 |
| 28 |
24095863 | Nicotine increases survival in human colon cancer cells treated with chemotherapeutic drugs. | 2013 Dec |
1 |
| 29 |
23108049 | DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins. | 2012 Nov 30 |
1 |
| 30 |
21475874 | AKT plays a pivotal role in the acquisition of resistance to 5-fluorouracil in human squamous carcinoma cells. | 2009 Jul-Aug |
2 |
| 31 |
17054996 | Mitogen-activated protein kinases and chemoresistance in pancreatic cancer cells. | 2006 Dec |
2 |
| 32 |
9824638 | Activation of MAP kinases by 5-fluorouracil in a 5-fluorouracil-resistant variant human cell line derived from a KT breast cancer cell line. | 1998 Dec |
1 |