Title : Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87.

Pub. Date : 2015 Apr 20

PMID : 25826088






1 Functional Relationships(s)
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1 Stabilization of Bcl-2 protein by paxillin (PXN)-mediated ERK activation was recently reported to cause an unfavorable response to 5-Fluorouracil-based chemotherapy. Fluorouracil mitogen-activated protein kinase 1 Homo sapiens