| 1 |
32796651 | Heat Shock Protein 90 (Hsp90)-Inhibitor-Luminespib-Loaded-Protein-Based Nanoformulation for Cancer Therapy. | 2020 Aug 11 |
1 |
| 2 |
31113013 | Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage. | 2019 May 21 |
6 |
| 3 |
26858237 | Hsp90 Inhibition Results in Glucocorticoid Receptor Degradation in Association with Increased Sensitivity to Paclitaxel in Triple-Negative Breast Cancer. | 2016 Apr |
1 |
| 4 |
27321499 | Re: First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors. | 2016 Jul |
1 |
| 5 |
23886587 | The HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin modulates radiosensitivity by downregulating serine/threonine kinase 38 via Sp1 inhibition. | 2013 Nov |
1 |
| 6 |
23650580 | The Hsp90 inhibitor 17-AAG represses calcium-induced cytokeratin 1 and 10 expression in HaCaT keratinocytes. | 2012 |
1 |
| 7 |
21106982 | The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78. | 2011 Jan 27 |
1 |
| 8 |
19662650 | BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy. | 2010 Mar 1 |
1 |
| 9 |
19809428 | Inhibition of constitutive and cxc-chemokine-induced NF-kappaB activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells. | 2009 Nov 3 |
1 |
| 10 |
19860734 | Ansamycin inhibitors of Hsp90: nature's prototype for anti-chaperone therapy. | 2009 |
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| 11 |
19952119 | The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo. | 2009 Dec |
2 |
| 12 |
18683558 | [The genes associated with geldanamycin inhibiting replication of herpes simplex virus type 1]. | 2008 May |
2 |
| 13 |
17079230 | The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells. | 2007 Jan 5 |
2 |
| 14 |
17131314 | Dimeric ansamycins--a new class of antitumor Hsp90 modulators with prolonged inhibitory activity. | 2007 Feb 15 |
2 |
| 15 |
17475647 | BAG3, a host cochaperone, facilitates varicella-zoster virus replication. | 2007 Jul |
1 |
| 16 |
17662999 | Mechanistic studies on Hsp90 inhibition by ansamycin derivatives. | 2007 Sep 14 |
3 |
| 17 |
16842157 | Hsp90: a novel target for cancer therapy. | 2006 |
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| 18 |
15897590 | Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo. | 2005 May 15 |
2 |
| 19 |
16004589 | Heat-shock protein 90 inhibitors in antineoplastic therapy: is it all wrapped up? | 2005 Jun |
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| 20 |
15001580 | Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling. | 2004 May 7 |
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| 21 |
15141013 | Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity. | 2004 May |
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| 22 |
15202892 | Biotinylated geldanamycin. | 2004 Jun 25 |
1 |
| 23 |
12574167 | ErbB2 degradation mediated by the co-chaperone protein CHIP. | 2003 Apr 18 |
1 |
| 24 |
12771028 | Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells. | 2003 May |
1 |
| 25 |
12890735 | Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation. | 2003 Dec |
1 |
| 26 |
14695217 | Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity. | 2003 Dec 15 |
2 |
| 27 |
11983711 | Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase. | 2002 Jul 12 |
3 |
| 28 |
12036925 | Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3'-kinase-AKT-dependent pathway. | 2002 Jun 1 |
1 |
| 29 |
11306472 | Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells. | 2001 Apr 1 |
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| 30 |
11489796 | Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. | 2001 Aug |
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| 31 |
10919672 | Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest. | 2000 Jul 15 |
2 |
| 32 |
9843494 | Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. | 1998 Dec 1 |
1 |
| 33 |
9228040 | The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin. | 1997 Jul 25 |
2 |
| 34 |
8962087 | Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90. | 1996 Dec 10 |
2 |