Acetaldehyde

aldehyde dehydrogenase 2 family member ; Homo sapiens







269 Article(s)
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1 34940794 A commentary on the paper: 'Evaluation of spice and herb as phytoderived selective modulators of human retinaldehyde dehydrogenases using a simple in vitro method'. 2022 Jan 28 1
2 35344413 ALDH2 Expression, Alcohol Intake and Semen Parameters among East Asian Men. 2022 Mar 28 1
3 32480415 Comprehensive analysis reveals distinct mutational signature and its mechanistic insights of alcohol consumption in human cancers. 2021 May 20 1
4 33283290 Association Between the Aldehyde Dehydrogenase-2 rs671 G>A Polymorphism and Head and Neck Cancer Susceptibility: A Meta-Analysis in East Asians. 2021 Feb 2
5 33388347 Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. 2021 Mar 1
6 33592568 Generation of induced pluripotent stem cells FIRDIi001-A from a Taiwanese subject carrying ALDH2 pE487K mutation. 2021 Apr 1
7 33744437 Development of new disulfiram analogues as ALDH1a1-selective inhibitors. 2021 May 15 2
8 33750341 Association between ALDH2 polymorphism and esophageal cancer risk in South Koreans: a case-control study. 2021 Mar 9 1
9 34010294 Acetaldehyde breath test as a cancer risk marker in patients with esophageal and hypopharyngeal squamous cell carcinoma. 2021 1
10 34056354 Enhancement of Solubility, Purification, and Inclusion Body Refolding of Active Human Mitochondrial Aldehyde Dehydrogenase 2. 2021 May 11 1
11 34070917 Regulation of Alcohol and Acetaldehyde Metabolism by a Mixture of Lactobacillus and Bifidobacterium Species in Human. 2021 May 30 1
12 34211048 Acetaldehyde exposure underlies functional defects in monocytes induced by excessive alcohol consumption. 2021 Jul 1 1
13 34221859 The role of ALDH2 in tumorigenesis and tumor progression: Targeting ALDH2 as a potential cancer treatment. 2021 Jun 2
14 34260573 Interaction between ALDH2 rs671 and life habits affects the risk of hypertension in Koreans: A STROBE observational study. 2021 Jul 16 1
15 34351898 Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism. 2021 Aug 3
16 34439848 Acetaldehyde Enhances Alcohol Sensitivity and Protects against Alcoholism: Evidence from Alcohol Metabolism in Subjects with Variant ALDH2*2 Gene Allele. 2021 Aug 10 1
17 34441974 Ethnic Differences in Serum Levels of microRNAs Potentially Regulating Alcohol Dehydrogenase 1B and Aldehyde Dehydrogenase 2. 2021 Aug 19 2
18 34528981 Intake of Lactobacillus rhamnosus GG (LGG) fermented milk before drinking alcohol reduces acetaldehyde levels and duration of flushing in drinkers with wild-type and heterozygous mutant ALDH2: a randomized, blinded crossover controlled trial. 2021 Oct 19 4
19 31204364 Alcohol Drinking and Bladder Cancer Risk From a Pooled Analysis of Ten Cohort Studies in Japan. 2020 Jul 7 1
20 31801381 Systemic Adeno-Associated Virus-Mediated Gene Therapy Prevents the Multiorgan Disorders Associated with Aldehyde Dehydrogenase 2 Deficiency and Chronic Ethanol Ingestion. 2020 Feb 3
21 32005715 Across-Site Differences in the Mechanism of Alcohol-Induced Digestive Tract Carcinogenesis: An Evaluation by Mediation Analysis. 2020 Apr 1 1
22 32140062 Aldehyde Dehydrogenase, Liver Disease and Cancer. 2020 3
23 32403082 Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes' toxicity. 2020 May 2
24 32681823 E487K-Induced Disorder in Functionally Relevant Dynamics of Mitochondrial Aldehyde Dehydrogenase 2. 2020 Aug 4 2
25 32687612 Interaction of Ethanol and Oral ANS-6637, a Selective ALDH2 Inhibitor in Males: A Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Cohort Study. 2020 Sep 2
26 32775346 Local Acetaldehyde: Its Key Role in Alcohol-Related Oropharyngeal Cancer. 2020 Jun 8
27 32850324 Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway. 2020 2
28 29509552 Effects of "Essential AD2" Supplement on Blood Acetaldehyde Levels in Individuals Who Have Aldehyde Dehydrogenase (ALDH2) Deficiency. 2019 Sep/Oct 7
29 30121625 Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids. 2019 Jul 2
30 30641047 A physiological concentration of luteolin induces phase II drug-metabolizing enzymes through the ERK1/2 signaling pathway in HepG2 cells. 2019 Mar 15 1
31 30931596 [Alcoholic liver disease: the roles of genetic-epigenetic factors and the effect of abstinence]. 2019 Apr 1
32 31066241 The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium. 2019 Jun 2
33 31114208 Aldehyde dehydrogenase 2 rs671G>A polymorphism and ischemic stroke risk in Chinese population: a meta-analysis. 2019 2
34 31283017 Different Effects of Knockouts in ALDH2 and ACSS2 on Embryonic Stem Cell Differentiation. 2019 Sep 2
35 31368097 ALDH2 and Cardiovascular Disease. 2019 1
36 31368105 ALDH2 and Stroke: A Systematic Review of the Evidence. 2019 1
37 31368106 Targeting ALDH2 in Atherosclerosis: Molecular Mechanisms and Therapeutic Opportunities. 2019 2
38 31368108 ALDH2 Polymorphism and Ethanol Consumption: A Genetic-Environmental Interaction in Carcinogenesis. 2019 3
39 31833292 Relationship between Blood Acetaldehyde Concentration and Psychomotor Function of Individuals with Different ALDH2 Genotypes after Alcohol Consumption. 2019 Oct 2
40 29247577 Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium. 2018 Feb 3
41 29248712 Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma. 2018 May 1 1
42 29303995 Local Acetaldehyde-An Essential Role in Alcohol-Related Upper Gastrointestinal Tract Carcinogenesis. 2018 Jan 5 1
43 29380601 Fiber-Optic Bio-sniffer (Biochemical Gas Sensor) Using Reverse Reaction of Alcohol Dehydrogenase for Exhaled Acetaldehyde. 2018 Feb 23 2
44 29431026 The potential of aldehyde dehydrogenase 2 as a therapeutic target in cardiovascular disease. 2018 Mar 1
45 29582627 ADH1B, ALDH2, GSTM1 and GSTT1 Gene Polymorphic Frequencies among Alcoholics and Controls in the Arcadian Population of Central India 2018 Mar 27 1
46 29616362 Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replication and mediation analysis. 2018 Nov 2
47 29623947 Genetic Polymorphisms of the Mitochondrial Aldehyde Dehydrogenase ALDH2 Gene in a Large Ethnic Hakka Population in Southern China. 2018 Apr 6 1
48 29651717 Alcohol Metabolic Inefficiency: Structural Characterization of Polymorphism-Induced ALDH2 Dysfunctionality and Allosteric Site Identification for Design of Potential Wildtype Reactivators. 2018 Jun 1
49 26212265 ALDH2---The Genetic Polymorphism and Enzymatic Activity Regulation: Their Epidemiologic and Clinical Implications. 2017 2
50 28027570 Aldehyde dehydrogenase-2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP-activated protein kinase signaling in mice. 2017 May 2