Title : E487K-Induced Disorder in Functionally Relevant Dynamics of Mitochondrial Aldehyde Dehydrogenase 2.

Pub. Date : 2020 Aug 4

PMID : 32681823






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mitochondrial aldehyde dehydrogenase 2 (ALDH2), which is a homotetramer assembled by two equivalent dimers, is an important enzyme that metabolizes ethanol-derived acetaldehyde to acetate in a coenzyme-dependent manner. Acetaldehyde aldehyde dehydrogenase 2 family member Homo sapiens
2 The highly reactive acetaldehyde exhibits a toxic effect, indicating that the proper functioning of ALDH2 is essential to counteract aldehyde-associated diseases. Acetaldehyde aldehyde dehydrogenase 2 family member Homo sapiens