lysophosphatidic acid

lysophosphatidic acid receptor 1 ; Mus musculus







107 Article(s)
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51 25701366 Lysophosphatidic acid receptor 1 antagonist ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis. 2015 Jul 2
52 26090649 The lysophosphatidic acid receptor LPA4 regulates hematopoiesis-supporting activity of bone marrow stromal cells. 2015 Jun 19 2
53 26180199 Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury. 2015 Jul 15 2
54 23775489 Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors. 2014 Sep 2
55 24249637 Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase. 2014 Feb 2
56 24251962 Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts. 2014 Jan 3
57 24429286 Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity. 2014 Mar 7 2
58 24632199 Lysophosphatidic acid receptor-5 negatively regulates cellular responses in mouse fibroblast 3T3 cells. 2014 Apr 4 2
59 24829209 Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. 2014 Jun 17 1
60 25078448 Application of in utero electroporation of G-protein coupled receptor (GPCR) genes, for subcellular localization of hardly identifiable GPCR in mouse cerebral cortex. 2014 Jul 2
61 25131845 Lysophosphatidic acid stimulates cell migration of satellite cells. A role for the sphingosine kinase/sphingosine 1-phosphate axis. 2014 Oct 1
62 25411045 Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice. 2014 Nov 19 5
63 23322166 LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation. 2013 May 3
64 23478264 Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure. 2013 May 1
65 23666827 Necessity of lysophosphatidic acid receptor 1 for development of arthritis. 2013 Aug 4
66 23909436 Downregulation of activation factors of endothelia and fibroblasts via lysophosphatidic acid signaling in a mouse lung cancer LL/2 cell line. 2013 Oct 2
67 24115248 Lysophosphatidic acid (LPA) and its receptor, LPA1 , influence embryonic schwann cell migration, myelination, and cell-to-axon segregation. 2013 Dec 4
68 24175745 Development of lysophosphatidic acid pathway modulators as therapies for fibrosis. 2013 Oct 2
69 21887497 Attenuation of cocaine-induced conditioned locomotion is associated with altered expression of hippocampal glutamate receptors in mice lacking LPA1 receptors. 2012 Mar 1
70 22015657 Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. 2012 Jan 1
71 22200658 Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis. 2012 Apr 1
72 22461625 Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain. 2012 May 18 2
73 21159750 Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist. 2011 Mar 3
74 21222547 Lysophosphatidic acid receptor agonists and antagonists (WO2010051053). 2011 Feb 1
75 21302283 LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. 2011 Nov 2
76 20069565 LPA induces osteoblast differentiation through interplay of two receptors: LPA1 and LPA4. 2010 Mar 1 4
77 20123931 Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain. 2010 May 1
78 20230855 LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid. 2010 Oct 2
79 20826223 Effects of lysophosphatidic acid on the in vitro proliferation and differentiation of a novel porcine preadipocyte cell line. 2010 Dec 2
80 21042747 Effects of lysophosphatidic acid and its receptors LPA⅓ on radiation pneumonitis. 2010 Dec 2
81 19912636 Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain. 2009 Nov 13 2
82 19930563 Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma. 2009 Nov 20 2
83 17692995 Lysophosphatidic acid stimulates astrocyte proliferation through LPA1. 2008 Jan 3
84 18066075 The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. 2008 Jan 1
85 18089565 Different mechanisms regulate lysophosphatidic acid (LPA)-dependent versus phorbol ester-dependent internalization of the LPA1 receptor. 2008 Feb 29 4
86 18198181 Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation. 2008 Mar 21 3
87 18261210 Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain. 2008 Feb 8 4
88 18280050 Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid. 2008 Mar 18 3
89 18448840 Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling. 2008 Aug 1
90 18703779 Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. 2008 Sep 12 2
91 18708146 Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus. 2008 Nov 2
92 17056154 Lysophosphatidic acid stimulates neuronal differentiation of cortical neuroblasts through the LPA1-G(i/o) pathway. 2007 Jan 1
93 18003779 LPA1 receptor activation promotes renal interstitial fibrosis. 2007 Dec 1
94 16404130 Lysophosphatidic acid (LPA) induces plasma exudation and histamine release in mice via LPA receptors. 2006 Jan 2
95 16487757 Lysophosphatidic acid induces chemotaxis in MC3T3-E1 osteoblastic cells. 2006 Jul 1
96 15716590 Differential effects of lysolipids on steroid synthesis in cells expressing endogenous LPA2 receptor. 2005 May 1
97 16018581 Neurochemical changes in LPA1 receptor deficient mice--a putative model of schizophrenia. 2005 Mar 1
98 16263766 A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors. 2005 Nov 15 5
99 15599396 Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer. 2004 Dec 2
100 15684836 Lysophosphatidic acid induces clonal generation of mouse neurospheres via proliferation of Sca-1- and AC133-positive neural progenitors. 2004 Dec 1