Tyrosine

MET proto-oncogene, receptor tyrosine kinase ; Homo sapiens







98 Article(s)
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51 15265705 Sphingosine kinase activation regulates hepatocyte growth factor induced migration of endothelial cells. 2004 Aug 15 1
52 15288476 SU5416 is a potent inhibitor of hepatocyte growth factor receptor (c-Met) and blocks HGF-induced invasiveness of human HepG2 hepatoma cells. 2004 Aug 1
53 15301554 Oligomerization-dependent changes in the thermodynamic properties of the TPR-MET receptor tyrosine kinase. 2004 Aug 17 2
54 15530853 Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells. 2004 Dec 10 2
55 15588784 Pharmacokinetic study of recombinant human hepatocyte growth factor administered in a bolus intravenously or via portal vein. 2004 Nov 1
56 12520544 HGF/SF-met signaling in the control of branching morphogenesis and invasion. 2003 Feb 1 1
57 12594808 Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells. 2003 May 1 4
58 12845672 The HGF/SF antagonist NK4 reverses fibroblast- and HGF-induced prostate tumor growth and angiogenesis in vivo. 2003 Sep 1 1
59 12856716 Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin. 2003 3
60 12883706 Rho regulates the hepatocyte growth factor/scatter factor-stimulated cell motility of human oral squamous cell carcinoma cells. 2003 Sep-Oct 1
61 14559814 c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions. 2003 Oct 1 2
62 11839685 Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer. 2002 Feb 1
63 12115601 The impact of c-met/scatter factor receptor on dendritic cell migration. 2002 Jul 1
64 12183053 CD44 stimulation by fragmented hyaluronic acid induces upregulation and tyrosine phosphorylation of c-Met receptor protein in human chondrosarcoma cells. 2002 Aug 19 4
65 12500176 HGF regulation of RPE proliferation in an IL-1beta/retinal hole-induced rabbit model of PVR. 2002 Dec 20 2
66 12500177 MAP kinase and beta-catenin signaling in HGF induced RPE migration. 2002 Dec 20 5
67 12611639 Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer. 2002 Oct-Dec 2
68 11254878 HGF/SF modifies the interaction between its receptor c-Met, and the E-cadherin/catenin complex in prostate cancer cells. 2001 Apr 1
69 11267961 Critical role of extracellular signal-regulated kinase phosphorylation on menadione (vitamin K3) induced growth inhibition. 2001 Mar 15 1
70 11278639 Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions. 2001 Apr 27 1
71 11290563 c-MET expression in myofibroblasts: role in autocrine activation and prognostic significance in lung adenocarcinoma. 2001 Apr 1
72 11557528 HGF upregulates and modifies subcellular distribution of proteins in colon cancer cell enterocytic differentiation. 2001 Oct 1
73 11745410 Ganglioside GD1a inhibits HGF-induced motility and scattering of cancer cells through suppression of tyrosine phosphorylation of c-Met. 2001 Nov 1 3
74 10702398 Overexpression of the hepatocyte growth factor (HGF) receptor (Met) and presence of a truncated and activated intracellular HGF receptor fragment in locally aggressive/malignant human musculoskeletal tumors. 2000 Mar 1
75 10759945 c-met tyrosine kinase receptor expression is associated with abnormal beta-catenin expression and favourable prognostic factors in invasive breast carcinoma. 2000 Apr 2
76 11014955 Expression of constitutively active c-MET receptor in human choriocarcinoma. 2000 1
77 11123423 Critical role of extracellular signal-regulated kinase (ERK) phosphorylation in novel vitamin K analog-induced cell death. 2000 Dec 1
78 9888438 Hepatocyte growth factor receptor in human RPE cells: implications in proliferative vitreoretinopathy. 1999 Jan 2
79 10430176 Met overexpression confers HGF-dependent invasive phenotype to human thyroid carcinoma cells in vitro. 1999 Sep 1
80 10520577 Presence and tyrosine phosphorylation of c-met receptor in human sperm. 1999 Sep-Oct 5
81 10763917 Hepatocyte growth factor promotes migration of human hepatocellular carcinoma via phosphatidylinositol 3-kinase. 1999 2
82 9694510 Hepatocyte growth factor/scatter factor (HGF/SF) is produced by human bone marrow stromal cells and promotes proliferation, adhesion and survival of human hematopoietic progenitor cells (CD34+). 1998 Aug 1
83 9705867 Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor. 1998 Aug 10 1
84 9722511 Cooperative interaction between alpha- and beta-chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses. 1998 Sep 4 3
85 9020068 Fas-signaling and effects on receptor tyrosine kinase signal transduction in human breast epithelial cells. 1997 Jan 3 1
86 9136843 Developmental expression and functionality of hepatocyte growth factor and c-Met in human fetal digestive tissues. 1997 May 1
87 9524774 Role of HGF/SF and c-Met in morphogenesis and metastasis of epithelial cells. 1997 1
88 8601419 Hepatocyte growth factor (HGF)-induced cell migration is negatively modulated by epidermal growth factor through tyrosine phosphorylation of the HGF receptor. 1996 Mar 15 3
89 8906793 Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. 1996 Nov 14 1
90 7731718 The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein. 1995 Apr 20 1
91 8183564 Structural and functional domains critical for constitutive activation of the HGF-receptor (Met). 1994 Jun 2
92 8294430 Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase. 1994 Jan 21 1
93 7679901 Tyrosine phosphorylation of phospholipase C gamma in c-met/HGF receptor-stimulated hepatocytes: comparison with HepG2 hepatocarcinoma cells. 1993 Feb 15 2
94 8398897 Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells. 1993 Jul 1
95 1327117 Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains. 1992 Oct 13 5
96 1674365 c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase. 1991 Apr 1
97 1827664 Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. 1991 Apr 1
98 2111905 Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein. 1990 May 2