dsbs

MRE11 homolog, double strand break repair nuclease ; Homo sapiens







28 Article(s)
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1 35076389 Structure of the human ATM kinase and mechanism of Nbs1 binding. 2022 Jan 25 1
2 33789097 Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners. 2021 Mar 30 1
3 33918759 A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells. 2021 Apr 9 1
4 32313254 CRISPR off-target detection with DISCOVER-seq. 2020 May 1
5 33087279 Restoration of ligatable "clean" double-strand break ends is the rate-limiting step in the rejoining of ionizing-radiation-induced DNA breakage. 2020 Sep 1
6 30168750 Low-dose radiations derived from cone-beam CT induce transient DNA damage and persistent inflammatory reactions in stem cells from deciduous teeth. 2019 Jan 1
7 31231660 Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context. 2019 1
8 31353207 C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex. 2019 Sep 19 1
9 29420790 Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance. 2018 Apr 6 1
10 30510002 Sae2 antagonizes Rad9 accumulation at DNA double-strand breaks to attenuate checkpoint signaling and facilitate end resection. 2018 Dec 18 1
11 26743002 S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex. 2016 Mar 18 1
12 25486192 DNA end resection is needed for the repair of complex lesions in G1-phase human cells. 2014 2
13 23770241 The Ku heterodimer and the metabolism of single-ended DNA double-strand breaks. 2013 Jun 27 1
14 23912341 Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms. 2013 Dec 20 1
15 24297933 Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11. 2013 Dec 17 2
16 22131123 Impact of heterozygous c.657-661del, p.I171V and p.R215W mutations in NBN on nibrin functions. 2012 May 1
17 20081839 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. 2010 Feb 1
18 21150274 ATM activation in the presence of oxidative stress. 2010 Dec 15 1
19 21290468 Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells. 2010 Oct 2
20 20064462 CtIP links DNA double-strand break sensing to resection. 2009 Dec 25 1
21 18632984 Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex. 2008 Sep 1
22 16879433 Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation. 2006 Aug 2
23 15908798 The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM. 2005 Jun 1
24 14532133 Requirement of the MRN complex for ATM activation by DNA damage. 2003 Oct 15 1
25 14657032 The Mre11 complex is required for ATM activation and the G2/M checkpoint. 2003 Dec 15 2
26 11832209 The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. 2002 Jan 25 1
27 11418077 Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism of radiosensitization by heat. 2001 Jul 1
28 11533665 Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex. 2001 Sep 1