birinapant

alkaline phosphatase, intestinal ; Homo sapiens







12 Article(s)
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1 33323457 Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway-Dependent Apoptosis. 2021 Feb 1
2 33660894 Development of a protein signature to enable clinical positioning of IAP inhibitors in colorectal cancer. 2021 Sep 1
3 33826739 SMAC Mimetic/IAP Inhibitor Birinapant Enhances Radiosensitivity of Glioblastoma Multiforme. 2021 Jun 1 1
4 32081986 Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism. 2020 Aug 1
5 33257690 Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant. 2020 Nov 30 1
6 30778852 The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival. 2019 Jun 1
7 29500433 Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711. 2018 Nov 3
8 28337955 Examining the In Vitro Efficacy of the IAP Antagonist Birinapant as a Single Agent or in Combination With Dacarbazine to Induce Melanoma Cell Death. 2017 Nov 2 2
9 29375545 Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses. 2017 1
10 27194727 The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia. 2016 May 18 1
11 27520705 IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis. 2016 Aug 12 2
12 23225169 Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism. 2013 Jan 2