Title : The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

Pub. Date : 2015 Oct

PMID : 26173855






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The initial UCP2 down-regulation was paralleled by mitochondrial inner membrane potential (mMP) depolarization and increased mitochondrial reactive oxygen species production. Reactive Oxygen Species uncoupling protein 2 Homo sapiens
2 The key role of UCP2 in controlling mMP and reactive oxygen species production was confirmed by both pharmacological inhibition and down-regulation by RNA interference. Reactive Oxygen Species uncoupling protein 2 Homo sapiens