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33600922 | Triptolide and atorvastatin synergistically promote hepatotoxicity in cultured hepatocytes and female Sprague-Dawley rats by inhibiting pregnane X receptor-mediated transcriptional activation of CYP3A4. | 2021 May 15 |
1 |
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30374997 | A sensitive LC-MS/MS method for the determination of triptolide and its application to pharmacokinetic research in rats. | 2019 Mar |
1 |
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29283173 | CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats. | 2018 Aug |
3 |
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24486211 | Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats. | 2014 Mar 14 |
1 |
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24910460 | Role of CYP3A in regulating hepatic clearance and hepatotoxicity of triptolide in rat liver microsomes and sandwich-cultured hepatocytes. | 2014 Sep |
3 |
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24133982 | In vivo effect of triptolide combined with glycyrrhetinic acid on rat cytochrome P450 enzymes. | 2013 Jul |
3 |
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21596114 | Knockout of hepatic P450 reductase aggravates triptolide-induced toxicity. | 2011 Aug 10 |
1 |
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20223271 | Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats. | 2010 Apr 30 |
1 |