Pub. Date : 2013 Jul
PMID : 24133982
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Because TP is mainly metabolized by CYP3A2 in male rats, the present work indicated that TP-induced increase of CYP3A activity might be an important reason for the rapidly metabolic clearance of TP in rat liver, and GA can reduce the hepatotoxicity of TP by promoting its hepatic metabolic clearance. | triptolide | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |
| 2 | Because TP is mainly metabolized by CYP3A2 in male rats, the present work indicated that TP-induced increase of CYP3A activity might be an important reason for the rapidly metabolic clearance of TP in rat liver, and GA can reduce the hepatotoxicity of TP by promoting its hepatic metabolic clearance. | triptolide | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |
| 3 | Because TP is mainly metabolized by CYP3A2 in male rats, the present work indicated that TP-induced increase of CYP3A activity might be an important reason for the rapidly metabolic clearance of TP in rat liver, and GA can reduce the hepatotoxicity of TP by promoting its hepatic metabolic clearance. | triptolide | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |