Title : [Effect of Bmi-1 on Multidrug Resistance in K562/ADR Cells and Its Mechanisms].

Pub. Date : 2020 Jun

PMID : 32552933






2 Functional Relationships(s)
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1 After K562/ADR cells were treated with PI3K/AKT pathway inhibitor LY294002, the protein expressions of NF-kappaB and P-gp were analyzed to determine the regulation of AKT on the expression of NF-kappaB and P-gp. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one nuclear factor kappa B subunit 1 Homo sapiens
2 The protein expressions of p-AKT, P-gp and the activity of NF-kappaB were inhibited significantly by using PI3K/AKT inhibitor LY294002 (P<0.05). 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one nuclear factor kappa B subunit 1 Homo sapiens