Irinotecan

tyrosyl-DNA phosphodiesterase 1 ; Homo sapiens







10 Article(s)
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Pub. Year
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1 34300575 A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors. 2021 Jul 15 2
2 33263997 Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I. 2020 Dec 16 2
3 31878088 Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy. 2019 Dec 23 2
4 30191738 Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy. 2018 Dec 1
5 25522766 Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan. 2015 Feb 2
6 23913164 TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells. 2013 Oct 2
7 19604089 Pharmacodynamic genes do not influence risk of neutropenia in cancer patients treated with moderately high-dose irinotecan. 2009 Jul 1
8 19883083 4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors. 2009 Nov 26 1
9 18347181 Irinotecan pharmacogenetics: influence of pharmacodynamic genes. 2008 Mar 15 1
10 20301284 Spinocerebellar Ataxia with Axonal Neuropathy, Autosomal Recessive – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY 1993 1