Title : Irinotecan pharmacogenetics: influence of pharmacodynamic genes.

Pub. Date : 2008 Mar 15

PMID : 18347181






1 Functional Relationships(s)
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Protein Name
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1 CDC45L, NFKB1, PARP1, TDP1, and XRCC1 have been shown to influence the cytotoxic action of camptothecins, including irinotecan. Irinotecan tyrosyl-DNA phosphodiesterase 1 Homo sapiens