Title : Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy.

Pub. Date : 2018 Dec

PMID : 30191738






1 Functional Relationships(s)
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Protein Name
Organism
1 TDP1 plays an essential role in the resistance of cancer cells to currently used antitumour drugs based on Top1 inhibitors such as topotecan and irinotecan. Irinotecan tyrosyl-DNA phosphodiesterase 1 Homo sapiens