trichostatin A

cyclin dependent kinase inhibitor 1A ; Homo sapiens







77 Article(s)
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51 12782595 Histone deacetylase inhibitors activate p21(WAF1) expression via ATM. 2003 Jun 1 2
52 12806965 [Gene-regulating chemoprevention against cancer--as a model for "molecular-targeting prevention" of cancer]. 2003 May 2
53 14502645 Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells. 2003 Oct 3
54 14521905 Functional interplay between modulation of histone deacetylase activity and its regulatory role in G2-M transition. 2003 Oct 17 9
55 14529481 The discovery of NVP-LAQ824: from concept to clinic. 2003 Nov 1
56 14529564 Oestrogen receptor alpha increases p21(WAF1/CIP1) gene expression and the antiproliferative activity of histone deacetylase inhibitors in human breast cancer cells. 2003 Oct 3
57 14599803 A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis. 2003 Nov 2
58 14623092 p15(INK4b) in HDAC inhibitor-induced growth arrest. 2003 Nov 20 1
59 21432092 Histone deacetylase inhibitors -Promising agents for 'gene-regulating chemoprevention' and 'molecular-targeting prevention' of cancer-. 2003 Nov 6
60 11831887 Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. 2002 Feb 14 1
61 11948134 Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. 2002 Apr 2
62 12479699 Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins. 2002 Nov 3
63 11368530 p21 gene regulation during enterocyte differentiation. 2001 Jun 1 1
64 11754398 Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. 2001 Nov 2
65 11908866 Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. 2001 2
66 10625687 p300 collaborates with Sp1 and Sp3 in p21(waf1/cip1) promoter activation induced by histone deacetylase inhibitor. 2000 Jan 14 4
67 10746741 Trichostatin A modulates expression of p21waf1/cip1, Bcl-xL, ID1, ID2, ID3, CRAB2, GATA-2, hsp86 and TFIID/TAFII31 mRNA in human lung adenocarcinoma cells. 2000 Feb 1
68 11093826 Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell lines. 2000 Dec 15 2
69 11132966 Mechanism of cell cycle arrest caused by histone deacetylase inhibitors in human carcinoma cells. 2000 Oct 4
70 11216497 Butyrate as a model for "gene-regulating chemoprevention and chemotherapy.". 2000 2
71 10066455 Cloning of a GADD34-like gene that interacts with the zinc-finger transcription factor which binds to the p21(WAF) promoter. 1999 Mar 5 4
72 10485470 Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor. 1999 Sep 1 9
73 10585285 IGF-II enhances trichostatin A-induced TGFbeta1 and p21(Waf1,Cip1, sdi1) expression in Hep3B cells. 1999 Dec 15 9
74 10667218 Histone deacetylase inhibitor activates the p21/WAF1/Cip1 gene promoter through the Sp1 sites. 1999 11
75 9618491 p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. 1998 Jun 9 1
76 9781835 Identification of active substances from Streptomyces culture fluids using p53-independent expression of p21/WAF1/Cip1 gene and their mode of action. 1998 Sep 2
77 9405248 Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites. 1997 Dec 8 6