Dopamine

nuclear receptor subfamily 4, group A, member 2 ; Mus musculus







71 Article(s)
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1 35593070 NURR1-deficient mice have age- and sex-specific behavioral phenotypes. 2022 May 20 7
2 32919409 Transgenerational modification of dopaminergic dysfunctions induced by maternal immune activation. 2021 Jan 1
3 33991560 Nurr1 deficiency shortens free running period, enhances photoentrainment to phase advance, and disrupts circadian cycling of the dopamine neuron phenotype. 2021 Aug 6 3
4 33994958 Quantitative Immunohistochemistry to Measure Regional Expression of Nurr1 in the Brain and the Effect of the Nurr1 Heterozygous Genotype. 2021 1
5 31455763 NURR1 deficiency is associated to ADHD-like phenotypes in mice. 2019 Aug 27 2
6 31850343 Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification. 2019 1
7 29564810 Kir6.2 Deficiency Promotes Mesencephalic Neural Precursor Cell Differentiation via Regulating miR-133b/GDNF in a Parkinson's Disease Mouse Model. 2018 Nov 1
8 29626009 The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced Parkinsonism. 2018 Jun 2
9 26803497 Directed Differentiation of Dopamine-Secreting Cells from Nurr1/GPX1 Expressing Murine Embryonic Stem Cells Cultured on Matrigel-Coated PCL Scaffolds. 2017 Mar 1
10 27771535 Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein. 2017 Jan 6 1
11 28989991 Region Specific Effects of Aging and the Nurr1-Null Heterozygous Genotype on Dopamine Neurotransmission. 2017 Jun 11
12 27432537 Directed differentiation of postnatal hippocampal neural stem cells generates nuclear receptor related‑1 protein‑ and tyrosine hydroxylase‑expressing cells. 2016 Sep 1
13 27532877 Nurr1 expression is modified by inflammation in microglia. 2016 Oct 19 2
14 29450128 Molecular characterization and analysis of the porcine NURR1 gene. 2016 Dec 2
15 25156412 Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease. 2015 Jan 1
16 25406165 Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease. 2015 Feb 1
17 25447275 Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes. 2015 Aug 1
18 25855987 Chronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity. 2015 2
19 26490873 Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression. 2015 Oct 21 2
20 23341612 Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons. 2013 Feb 5 3
21 21531044 Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's disease. 2012 May 6
22 21932041 NR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes. 2012 Mar 2
23 22328530 miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression. 2012 Apr 1 5
24 22483304 Anti-parkinsonian effects of Nurr1 activator in ubiquitin-proteasome system impairment induced animal model of Parkinson's disease. 2012 Sep 2
25 22514272 Cooperation of nuclear fibroblast growth factor receptor 1 and Nurr1 offers new interactive mechanism in postmitotic development of mesencephalic dopaminergic neurons. 2012 Jun 8 1
26 23240065 Restriction of neural precursor ability to respond to Nurr1 by early regional specification. 2012 1
27 21545404 Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency. 2011 Jul 1
28 21593433 Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models. 2011 Sep 1
29 21820432 Relationship between sensorimotor gating deficits and dopaminergic neuroanatomy in Nurr1-deficient mice. 2011 Nov 2
30 20175204 Rapid increase of Nurr1 mRNA expression in limbic and cortical brain structures related to coping with depression-like behavior in mice. 2010 Aug 1 1
31 19515692 Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons. 2009 Jul 3
32 20016108 Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. 2009 Dec 16 2
33 18420193 The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. 2008 Jun 10 2
34 18495356 Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy. 2008 Jun 23 1
35 18579122 Nurr1 deficiency predisposes to lactacystin-induced dopaminergic neuron injury in vitro and in vivo. 2008 Jul 30 2
36 18655117 Alterations in amphetamine-stimulated dopamine overflow due to the Nurr1-null heterozygous genotype and postweaning isolation. 2008 Oct 8
37 17394463 Regulation of GTP cyclohydrolase I expression by orphan receptor Nurr1 in cell culture and in vivo. 2007 Apr 2
38 17457314 Adult mice with reduced Nurr1 expression: an animal model for schizophrenia. 2007 Aug 3
39 16477036 Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype. 2006 Feb 21 1
40 16638018 Neuropilin1 is a direct downstream target of Nurr1 in the developing brain stem. 2006 Jun 1
41 16690213 Early postnatal isolation reduces dopamine levels, elevates dopamine turnover and specifically disrupts prepulse inhibition in Nurr1-null heterozygous mice. 2006 Jul 21 6
42 16782508 Reduced tyrosine hydroxylase and GTP cyclohydrolase mRNA expression, tyrosine hydroxylase activity, and associated neurochemical alterations in Nurr1-null heterozygous mice. 2006 Jun 30 5
43 16893530 Nur77 gene knockout alters dopamine neuron biochemical activity and dopamine turnover. 2006 Sep 15 1
44 15589522 Age-dependent dopaminergic dysfunction in Nurr1 knockout mice. 2005 Jan 1
45 15615863 Induction patterns of transcription factors of the nur family (nurr1, nur77, and nor-1) by typical and atypical antipsychotics in the mouse brain: implication for their mechanism of action. 2005 Apr 2
46 15691706 The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons. 2005 Feb 1
47 16126911 Nitric oxide mediates increased susceptibility to dopaminergic damage in Nurr1 heterozygous mice. 2005 Sep 1
48 14742729 Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice. 2004 Apr 1 3
49 12678688 The control of dopamine neuron development, function and survival: insights from transgenic mice and the relevance to human disease. 2003 May 3
50 12814373 Decreased ethanol preference and wheel running in Nurr1-deficient mice. 2003 Jun 3