Heparin

fibroblast growth factor 1 ; Homo sapiens







156 Article(s)
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1 34933004 Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent Dyes in the flexible N-Terminal region and a rigid β-turn region. 2022 Mar 1 2
2 33745974 Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1. 2021 Jun 1 2
3 34341408 Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor. 2021 Aug 2 1
4 34762427 Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding. 2021 Nov 25 10
5 32653371 Structural analysis of a glucoglucuronan derived from laminarin and the mechanisms of its anti-lung cancer activity. 2020 Nov 15 6
6 30667535 Molecular dynamics insights into protein-glycosaminoglycan systems from microsecond-scale simulations. 2019 Jul 2
7 31271519 Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation. 2019 Aug 1
8 31420170 Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity. 2019 Oct 15 2
9 31578149 Heparinized silk fibroin hydrogels loading FGF1 promote the wound healing in rats with full-thickness skin excision. 2019 Oct 2 1
10 29556563 Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor. 2018 Mar 4
11 29645318 Investigating the dynamics and polyanion binding sites of fibroblast growth factor-1 using hydrogen-deuterium exchange mass spectrometry. 2018 Jun 4
12 29812912 Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4. 2018 Jul 3 1
13 30031837 Probing the role of proline -135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor. 2018 Sep 15 6
14 30271699 Impact of Temperature on Heparin and Protein Interactions. 2018 2
15 28181797 A Thermosensitive Heparin-Poloxamer Hydrogel Bridges aFGF to Treat Spinal Cord Injury. 2017 Mar 1 1
16 28629128 Interactions between a Heparin Trisaccharide Library and FGF-1 Analyzed by NMR Methods. 2017 Jun 17 1
17 29016740 A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration. 2017 Nov 1 13
18 29091276 Simple and Efficient Purification of Recombinant Proteins Using the Heparin-Binding Affinity Tag. 2017 Nov 1 1
19 26138239 Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis. 2015 Jul 3 2
20 24595027 Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1). 2014 2
21 25043635 Probing structurally altered and aggregated states of therapeutically relevant proteins using GroEL coupled to bio-layer interferometry. 2014 Oct 2
22 28890953 The Effects of Metal Ions on Heparin/Heparin Sulfate-Protein Interactions. 2014 3
23 22687193 Structural stability of human fibroblast growth factor-1 is essential for protective effects against radiation-induced intestinal damage. 2013 Feb 1 2
24 23601319 Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes. 2013 Apr 16 4
25 24178304 3D structure of a heparin mimetic analogue of a FGF-1 activator. A NMR and molecular modelling study. 2013 Dec 21 1
26 22113934 An empirical phase diagram approach to investigate conformational stability of "second-generation" functional mutants of acidic fibroblast growth factor-1. 2012 Mar 3
27 23019343 Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity. 2012 Nov 16 3
28 23133616 Pharmacokinetic properties of 2nd-generation fibroblast growth factor-1 mutants for therapeutic application. 2012 3
29 20827464 Heparin-immobilized microspheres for the capture of cytokines. 2011 Jan 3
30 21185801 Strategy for fluorescent labeling of human acidic fibroblast growth factor without impairment of mitogenic activity: a bona fide tracer. 2011 Apr 1 3
31 20416374 Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer. 2010 Jul 1
32 19034645 A surface plasmon resonance-based solution affinity assay for heparan sulfate-binding proteins. 2009 Jul 1
33 19400583 Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution. 2009 Jun 9 1
34 19574212 Increased protein stability of FGF1 can compensate for its reduced affinity for heparin. 2009 Sep 11 9
35 19810698 Analysis of the dynamics of assembly and structural impact for a histidine tagged FGF1-1.5 nm Au nanoparticle bioconjugate. 2009 Nov 1
36 19819428 Synthesis of a heparan sulfate mimetic disaccharide with a conformationally locked residue from a common intermediate. 2009 Nov 23 1
37 17981035 Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides. 2008 Jan 1 1
38 18441324 Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling. 2008 Jun 27 2
39 18710495 Biologically active fibroblast growth factor 1 tagged with various epitopes. 2008 Jul 11 1
40 17094138 Effects of solutes on empirical phase diagrams of human fibroblast growth factor 1. 2007 Jun 2
41 16223363 Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin. 2006 Feb 1 2
42 16417632 HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. 2006 Jan 17 2
43 16766579 Acidic fibroblast growth factor decreases alpha-smooth muscle actin expression and induces apoptosis in human normal lung fibroblasts. 2006 Nov 1
44 16794256 Heparin and fibroblast growth factors affect surfactant protein gene expression in type II cells. 2006 Nov 1
45 16937240 Backbone dynamics of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue, by 15N NMR relaxation methods. 2006 Aug 1
46 16995857 Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue. 2006 Oct 5
47 17066397 Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions. 2006 Nov 24 1
48 15767480 Acidic fibroblast growth factor (FGF-1) and FGF receptor 1 signaling in human Y79 retinoblastoma. 2005 Mar 2
49 15839662 Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the (1)C(4) and (2)S(O) conformations of a bioactive heparin-like hexasaccharide. 2005 Apr 27 2
50 16039522 Chemical approaches to define the structure-activity relationship of heparin-like glycosaminoglycans. 2005 Jul 1