Heparin

fibroblast growth factor 1 ; Homo sapiens







156 Article(s)
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51 16126225 Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action. 2005 Sep 30 1
52 16173813 Bioactive thin film of acidic fibroblast growth factor fabricated by layer-by-layer assembly. 2005 Sep-Oct 1
53 16219767 Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes. 2005 Dec 23 6
54 14657241 Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism. 2004 Feb 1
55 14695513 The activation of fibroblast growth factors (FGFs) by glycosaminoglycans: influence of the sulfation pattern on the biological activity of FGF-1. 2004 Jan 3 1
56 15533444 Symmetric primary and tertiary structure mutations within a symmetric superfold: a solution, not a constraint, to achieve a foldable polypeptide. 2004 Nov 26 2
57 12656349 Surface plasmon resonance analysis to evaluate the importance of heparin sulfate groups' binding with human aFGF and bFGF. 2003 Jan-Feb 2
58 12692004 Low density lipoproteins interact with acidic fibroblast growth factor and modify its function. 2003 Apr 1 1
59 12756357 R136K fibroblast growth factor-1 mutant induces heparin-independent migration of endothelial cells through fibrin glue. 2003 May 2
60 14502551 Biospecific extraction and neutralization of anticoagulant heparin with fibroblast growth factors (FGF). 2003 Oct 3
61 11714710 Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes. 2002 Jan 25 1
62 11890696 Minimal heparin/heparan sulfate sequences for binding to fibroblast growth factor-1. 2002 Mar 22 3
63 12059036 Increase of acidic fibroblast growth factor in the brains of hamsters infected with either 263K or 139H strains of scrapie. 2002 Jun 2
64 12115937 Expression and biological effect of urodele fibroblast growth factor 1: relationship to limb regeneration. 2002 May 1 2
65 12484774 Investigation of the structural stability of the human acidic fibroblast growth factor by hydrogen-deuterium exchange. 2002 Dec 24 1
66 11241127 Construction and biological characterization of an HB-GAM/FGF-1 chimera for vascular tissue engineering. 2001 Mar 4
67 11457455 Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution. 2001 Jul 13 1
68 11724555 Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. 2001 Dec 4 3
69 11828504 The activation of fibroblast growth factors by heparin: synthesis, structure, and biological activity of heparin-like oligosaccharides. 2001 Sep 3 2
70 10664506 The S130K fibroblast growth factor-1 mutant induces heparin-independent proliferation and is resistant to thrombin degradation in fibrin glue. 2000 Feb 4
71 10835602 Engineering of an FGF-proteoglycan fusion protein with heparin-independent, mitogenic activity. 2000 Jun 1
72 10852713 Thermodynamic characterization of mutants of human fibroblast growth factor 1 with an increased physiological half-life. 2000 Jun 20 1
73 10860838 Ligand binding properties of binary complexes of heparin and immunoglobulin-like modules of FGF receptor 2. 2000 Jun 16 1
74 11032250 Selection of peptide ligands that bind to acid fibroblast growth factor. 2000 Jun 2
75 11043400 Growth factor-induced morphological, physiological and molecular characteristics in cerebral endothelial cells. 2000 Sep 1
76 11069186 Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. 2000 Oct 26 3
77 11087710 Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2. 2000 Nov 1
78 10051565 Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans. 1999 Mar 2 1
79 10070748 Solution structure of human acidic fibroblast growth factor and interaction with heparin-derived hexasaccharide. 1999 Jan 3
80 10226073 Acidic fibroblast growth factor induces an antifibrogenic phenotype in human lung fibroblasts. 1999 May 4
81 10336501 Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase. 1999 May 28 1
82 10404599 A dimeric ternary complex of FGFR [correction of FGFR1], heparin and FGF-1 leads to an 'electrostatic sandwich' model for heparin binding. 1999 Jun 15 1
83 10413500 Site-directed mutagenesis and molecular modeling identify a crucial amino acid in specifying the heparin affinity of FGF-1. 1999 Jul 20 7
84 10561907 Enhanced growth of megakaryocyte colonies in culture in the presence of heparin and fibroblast growth factor. 1999 Oct 1
85 9600090 Primary structure of ovine fibroblast growth factor-1 deduced by protein and cDNA analysis. 1998 May 8 1
86 9700949 Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis. 1998 Aug 1
87 9755102 Sulfation of extracellular matrices modifies growth factor effects on type II cells on laminin substrata. 1998 Oct 1
88 9843417 The glycine box: a determinant of specificity for fibroblast growth factor. 1998 Nov 24 1
89 9288226 Effects of acidic and basic fibroblast growth factors on cell proliferation in pleomorphic adenoma of the parotid gland. 1997 Jul 1
90 9466688 Heparan sulfate is required for interaction and activation of the epithelial cell fibroblast growth factor receptor-2IIIb with stromal-derived fibroblast growth factor-7. 1997 Nov-Dec 1
91 8591858 A novel chimeric fibroblast growth factor for liver parenchymal cells. 1996 Feb 2
92 8613463 Fibroblast growth factor and heparin protect endothelial cells from the effects of interleukin 1. 1996 May 2
93 8878902 Potentiation of the growth-stimulatory effects of aFGF by heparin in Rama 27 fibroblasts. 1996 Aug 1
94 8900171 Molecular modeling and deletion mutagenesis implicate the nuclear translocation sequence in structural integrity of fibroblast growth factor-1. 1996 Oct 25 2
95 9070372 Structure and function of fibroblast growth factor. 1996 Jul 1
96 24194252 Expression patterns of acidic and basic fibroblast growth factor in loach fish embryos. 1996 Aug 1
97 7493920 The cysteine residue responsible for the release of fibroblast growth factor-1 residues in a domain independent of the domain for phosphatidylserine binding. 1995 Dec 8 2
98 7536241 Deamidation of polyanion-stabilized acidic fibroblast growth factor. 1995 Jan 1
99 7537691 FGF-1 is a heparin-independent mitogen for rat hepatocytes. 1995 May 1
100 7592764 Analysis of putative heparin-binding domains of fibroblast growth factor-1. Using site-directed mutagenesis and peptide analogues. 1995 Oct 27 2