etomoxir

carnitine palmitoyltransferase 1A ; Homo sapiens







28 Article(s)
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1 32654140 Glioma cells survival depends both on fatty acid oxidation and on functional carnitine transport by SLC22A5. 2021 Mar 1
2 34052835 Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis. 2021 May 29 1
3 34167568 Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity. 2021 Jun 24 3
4 34213835 iRGD-modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation. 2021 Dec 1
5 34650679 ZLN005 protects against ischemia-reperfusion-induced kidney injury by mitigating oxidative stress through the restoration of mitochondrial fatty acid oxidation. 2021 2
6 31776920 Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells. 2020 2
7 31555131 Cigarette Smoke Reduces Fatty Acid Catabolism, Leading to Apoptosis in Lung Endothelial Cells: Implication for Pathogenesis of COPD. 2019 1
8 29528039 Berberine Protects Against Palmitate-Induced Apoptosis in Tubular Epithelial Cells by Promoting Fatty Acid Oxidation. 2018 Mar 12 2
9 29596410 Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation. 2018 Mar 2
10 29674640 The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. 2018 Apr 19 6
11 29721083 Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy. 2018 1
12 29754287 Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets. 2018 Aug 2
13 30043752 Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. 2018 Sep 4 1
14 30043753 Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation. 2018 Sep 4 1
15 30175155 A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation. 2018 1
16 30282046 Fatty Acid Oxidation in Macrophages and T Cells: Time for Reassessment? 2018 Oct 2 1
17 27739027 An indispensable role of CPT-1a to survive cancer cells during energy stress through rewiring cancer metabolism. 2016 Oct 13 2
18 25501281 Targeting prostate cancer cell metabolism: impact of hexokinase and CPT-1 enzymes. 2015 Apr 2
19 24488024 Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses. 2014 May 1
20 25122071 Lipid catabolism via CPT1 as a therapeutic target for prostate cancer. 2014 Oct 2
21 20820848 Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation. 2011 Apr 1
22 21745359 Lipotoxicity is glucose-dependent in INS-1E cells but not in human islets and MIN6 cells. 2011 Jul 11 1
23 17319797 A double-blind randomized multicentre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison with placebo in patients with moderate congestive heart failure: the ERGO (etomoxir for the recovery of glucose oxidation) study. 2007 Aug 2
24 16777940 Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels. 2006 Sep 1 1
25 17149674 Acute heart failure--basic pathomechanism and new drug targets. 2006 Nov 2
26 16225603 A new therapeutic approach to treat psoriasis by inhibition of fatty acid oxidation by Etomoxir. 2005 Nov 1
27 11866664 Therapeutic potential of CPT I inhibitors: cardiac gene transcription as a target. 2002 Mar 1
28 12075114 Etomoxir-induced oxidative stress in HepG2 cells detected by differential gene expression is confirmed biochemically. 2002 Jul 1