Pub. Date : 2014 Oct
PMID : 25122071
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Etomoxir is an irreversible inhibitor of the carnitine palmitoyltransferase (CPT1) enzyme that decreases beta oxidation in the mitochondria. | etomoxir | carnitine palmitoyltransferase 1A | Homo sapiens |
| 2 | Knockdown of CPT1A enzyme in LNCaP cells resulted in decreased palmitate oxidation but increased sensitivity to etomoxir, with inactivation of AKT kinase and activation of caspase-3. | etomoxir | carnitine palmitoyltransferase 1A | Homo sapiens |