1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 ; Mus musculus







73 Article(s)
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1 35466109 Effects of Subdiaphragmatic Vagotomy in the MPTP-induced Neurotoxicity in the Striatum and Colon of Mice. 2022 May 31 1
2 35625810 Toxic Exposure to Endocrine Disruptors Worsens Parkinson's Disease Progression through NRF2/HO-1 Alteration. 2022 May 5 1
3 34560239 Regulation of neurotoxicity in the striatum and colon of MPTP-induced Parkinson's disease mice by gut microbiome. 2021 Dec 2
4 31418048 MPTP-induced dopaminergic neurotoxicity in mouse brain is attenuated after subsequent intranasal administration of (R)-ketamine: a role of TrkB signaling. 2020 Jan 8
5 32387710 Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTP. 2020 Jun 21 1
6 32848705 Lactulose and Melibiose Attenuate MPTP-Induced Parkinson's Disease in Mice by Inhibition of Oxidative Stress, Reduction of Neuroinflammation and Up-Regulation of Autophagy. 2020 2
7 30590105 c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson's Disease. 2019 Feb 10 1
8 31105522 Lipostatic Mechanisms Preserving Cerebellar Lipids in MPTP-Treated Mice: Focus on Membrane Microdomains and Lipid-Related Gene Expression. 2019 3
9 31132231 Dietary intake of glucoraphanin prevents the reduction of dopamine transporter in the mouse striatum after repeated administration of MPTP. 2019 Sep 6
10 31445131 Total glucosides of paeony (TGP) extracted from Radix Paeoniae Alba exerts neuroprotective effects in MPTP-induced experimental parkinsonism by regulating the cAMP/PKA/CREB signaling pathway. 2019 Dec 5 2
11 31479418 Antibiotic-induced microbiome depletion protects against MPTP-induced dopaminergic neurotoxicity in the brain. 2019 Sep 3 2
12 31583052 Salidroside Protects Dopaminergic Neurons by Enhancing PINK1/Parkin-Mediated Mitophagy. 2019 1
13 29332269 Behavioral, Biochemical and Molecular Characterization of a Parkinson's Disease Mouse Model Using the Neurotoxin 2'-CH3-MPTP: A Novel Approach. 2018 Mar 1
14 28377118 Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss. 2017 May 2
15 28734031 Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway. 2017 Sep 2
16 28830769 Plasmalogen precursor mitigates striatal dopamine loss in MPTP mice. 2017 Nov 1 2
17 26827716 Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system. 2016 Mar 11 1
18 26828289 Neuroprotective effect of fucoidan from Turbinaria decurrens in MPTP intoxicated Parkinsonic mice. 2016 May 1
19 26959819 Plasmalogen Augmentation Reverses Striatal Dopamine Loss in MPTP Mice. 2016 2
20 25447236 Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits. 2015 Feb 1
21 25943481 Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease. 2015 Jul 23 1
22 26006269 The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson's disease. 2015 Oct 2
23 26203861 Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons. 2015 Jul 23 1
24 24648001 Wnt/β-catenin signaling is required to rescue midbrain dopaminergic progenitors and promote neurorepair in ageing mouse model of Parkinson's disease. 2014 Aug 1
25 24657313 Escin attenuates behavioral impairments, oxidative stress and inflammation in a chronic MPTP/probenecid mouse model of Parkinson's disease. 2014 Oct 17 2
26 24799940 Neuroprotective Effects of Jitai Tablet, a Traditional Chinese Medicine, on the MPTP-Induced Acute Model of Parkinson's Disease: Involvement of the Dopamine System. 2014 1
27 25064079 Neuroprotective effect of the chemical chaperone, trehalose in a chronic MPTP-induced Parkinson's disease mouse model. 2014 Sep 1
28 21788124 Neuronal or inducible nitric oxide synthase (NOS) expression level is not involved in the different susceptibility to nigro-striatal dopaminergic neurotoxicity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) between C57BL/6 and BALB/c mice. 2013 Jan 5
29 22281418 Involvement of monoamine oxidase-B in the acute neurotoxicity of MPTP in embryonic and newborn mice. 2013 May 4
30 23911879 Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease. 2013 Oct 24 1
31 22634505 Theaflavin ameliorates behavioral deficits, biochemical indices and monoamine transporters expression against subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease. 2012 Aug 30 2
32 22885234 Ginkgo biloba extract (EGb 761) modulates the expression of dopamine-related genes in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice. 2012 Oct 25 1
33 21185886 Loss of striatal dopaminergic terminals during the early stage in response to MPTP injection in C57BL/6 mice. 2011 Apr 2
34 21476268 [A comparative study of hemantane and amantadine effects on dopamine transporter expression in brain of normal and MPTP-treated C57BL/6 mice]. 2011 1
35 21092260 Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. 2010 Nov 23 1
36 19027004 Role of nuclear transcription factor kappa B (NF-kappaB) for MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine)-induced apoptosis in nigral neurons of mice. 2009 Feb 2
37 19319673 MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood. 2009 Jun 1
38 19520064 Effect of caffeine on the expression of cytochrome P450 1A2, adenosine A2A receptor and dopamine transporter in control and 1-methyl 4-phenyl 1, 2, 3, 6-tetrahydropyridine treated mouse striatum. 2009 Aug 4 2
39 19616025 MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters. 2009 Nov 5
40 19631714 Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice. 2009 Nov 13 2
41 19686731 Effects of a novel dopamine uptake inhibitor upon extracellular dopamine from superfused murine striatal tissue. 2009 Oct 1 4
42 17920944 Bak Foong protects dopaminergic neurons against MPTP-induced neurotoxicity by its anti-apoptotic activity. 2008 Jan 1
43 18054104 Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease. 2008 Feb 2
44 18235988 Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice. 2008 Jun 2
45 18420351 Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease. 2008 May 15 1
46 17486689 Toki-to protects dopaminergic neurons in the substantia nigra from neurotoxicity of MPTP in mice. 2007 Sep 3
47 17515828 Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice. 2007 Jul 1
48 17597311 Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP. 2007 Jul 10 2
49 16959318 In vivo modulation of the Parkinsonian phenotype by Nrf2. 2006 Dec 2
50 15499605 Selective alterations of gene expression in mice induced by MPTP. 2005 Jan 2