Title : Behavioral, Biochemical and Molecular Characterization of a Parkinson's Disease Mouse Model Using the Neurotoxin 2'-CH3-MPTP: A Novel Approach.

Pub. Date : 2018 Mar

PMID : 29332269






1 Functional Relationships(s)
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1 Interestingly, 2"-CH3-MPTP leads to increased DAT and MAO-B transcription, which could explain, respectively, its higher potency and the requirement of higher doses of MAO inhibitors to prevent nigrostriatal neuronal death when compared to MPTP. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus