| 1 |
33125148 | Role of RASA1 in cancer: A review and update (Review). | 2020 Dec |
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| 2 |
31041977 | Diversity of mechanisms in Ras-GAP catalysis of guanosine triphosphate hydrolysis revealed by molecular modeling. | 2019 May 15 |
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31611389 | KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis. | 2019 Oct 29 |
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| 4 |
26866994 | Enhancing Paradynamics for QM/MM Sampling of Enzymatic Reactions. | 2016 Mar 10 |
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| 5 |
27043216 | Reaction Mechanism of Guanosine Triphosphate Hydrolysis by the Vision-Related Protein Complex Arl3-RP2. | 2016 Apr 28 |
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| 6 |
27214270 | Theoretical vibrational spectroscopy of intermediates and the reaction mechanism of the guanosine triphosphate hydrolysis by the protein complex Ras-GAP. | 2016 Sep 5 |
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| 7 |
25663768 | MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways. | 2015 Feb 7 |
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| 8 |
25820867 | Computational characterization of the chemical step in the GTP hydrolysis by Ras-GAP for the wild-type and G13V mutated Ras. | 2015 Jun |
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| 9 |
26370130 | Why does mutation of Gln61 in Ras by the nitro analog NGln maintain activity of Ras-GAP in hydrolysis of guanosine triphosphate? | 2015 Nov |
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| 10 |
25202123 | MicroRNAs 206 and 21 cooperate to promote RAS-extracellular signal-regulated kinase signaling by suppressing the translation of RASA1 and SPRED1. | 2014 Nov 15 |
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| 11 |
25339142 | Modeling the role of G12V and G13V Ras mutations in the Ras-GAP-catalyzed hydrolysis reaction of guanosine triphosphate. | 2014 Nov 18 |
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| 12 |
24224811 | Kinetic mechanisms of mutation-dependent Harvey Ras activation and their relevance for the development of Costello syndrome. | 2013 Nov 26 |
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| 13 |
22664862 | Phosphoprotein associated with glycosphingolipid microdomains 1 inhibits the proliferation and invasion of human prostate cancer cells in vitro through suppression of Ras activation. | 2012 Aug |
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| 14 |
23236136 | Catalytic mechanism of a mammalian Rab·RabGAP complex in atomic detail. | 2012 Dec 26 |
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| 15 |
23650596 | Exploring potassium-dependent GTP hydrolysis in TEES family GTPases. | 2012 |
2 |
| 16 |
20018863 | Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics. | 2010 Feb 19 |
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| 17 |
19022332 | p120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling. | 2009 Mar |
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| 18 |
19321438 | Crystal structure of the GTPase-activating protein-related domain from IQGAP1. | 2009 May 29 |
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| 19 |
18682833 | A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death. | 2008 Aug 6 |
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| 20 |
17094109 | Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations. | 2007 Feb 1 |
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| 21 |
16757310 | Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis. | 2006 |
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| 22 |
15906320 | QM/MM modeling the Ras-GAP catalyzed hydrolysis of guanosine triphosphate. | 2005 Aug 15 |
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| 23 |
15917201 | RASA1: variable phenotype with capillary and arteriovenous malformations. | 2005 Jun |
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| 24 |
16052311 | Computational study of a transition state analog of phosphoryl transfer in the Ras-RasGAP complex: AlF(x) versus MgF3-. | 2005 Nov |
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| 25 |
15210132 | Quantum chemical modeling of the GTP hydrolysis by the RAS-GAP protein complex. | 2004 Jul 1 |
5 |
| 26 |
15292263 | Fourier transform infrared spectroscopy on the Rap.RapGAP reaction, GTPase activation without an arginine finger. | 2004 Oct 29 |
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| 27 |
15340059 | Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity. | 2004 Sep |
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| 28 |
17052120 | Signal processing at the Ras circuit: what shapes Ras activation patterns? | 2004 Jun |
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| 29 |
12787671 | Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP. | 2003 Jun 13 |
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| 30 |
11371635 | The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP. | 2001 May 22 |
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| 31 |
11566491 | Human breast cancer MDA-MB-231 cells fail to express the neurofibromin protein, lack its type I mRNA isoform and show accumulation of P-MAPK and activated Ras. | 2001 Oct 30 |
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| 32 |
9102473 | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. | 1997 Mar 7 |
2 |
| 33 |
9312123 | A new function of p120-GTPase-activating protein. Prevention of the guanine nucleotide exchange factor-stimulated nucleotide exchange on the active form of Ha-ras p21. | 1997 Oct 3 |
4 |
| 34 |
8621595 | Enhancement of protein kinase C-dependent O2 production in Epstein-Barr virus-transformed B lymphocytes by p120Ras-GAP antisense oligonucleotide. | 1996 Apr 19 |
2 |
| 35 |
8816504 | Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity. | 1996 Oct |
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| 36 |
8909796 | Control of ras activation. | 1996 |
2 |
| 37 |
7492562 | Kinetics of inorganic phosphate release during the interaction of p21ras with the GTPase-activating proteins, p120-GAP and neurofibromin. | 1995 Nov 28 |
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| 38 |
7499225 | A conserved region of c-Ha-Ras is required for efficient GTPase stimulation by GTPase activating protein but not neurofibromin. | 1995 Nov 17 |
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| 39 |
8607981 | Interactions between Ras and Raf: key regulatory proteins in cellular transformation. | 1995 Dec |
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| 40 |
8738474 | The role of ras GTPase activating protein in human tumorigenesis. | 1995 |
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| 41 |
7516336 | Incorporation of Rap 1b into the platelet cytoskeleton is dependent on thrombin activation and extracellular calcium. | 1994 Jun 24 |
1 |
| 42 |
7935432 | p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly. | 1994 Nov |
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| 43 |
8195713 | Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth. | 1994 Jun 1 |
1 |
| 44 |
8270251 | Genetic analysis of the catalytic domain of the GAP gene in human lung cancer cell lines. | 1994 Jan |
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| 45 |
8262937 | Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determining the transforming ability of ras. | 1993 Dec 25 |
2 |
| 46 |
8338843 | Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue. | 1993 Jul 27 |
2 |
| 47 |
1939245 | Rap1A antagonizes the ability of Ras and Ras-Gap to inhibit muscarinic K+ channels. | 1991 Nov 25 |
2 |
| 48 |
2115644 | Amino acid 61 is a determinant of sensitivity of rap proteins to the ras GTPase activating protein. | 1990 Jul |
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