| 1 |
33301355 | Endothelial S1P1 Signaling Counteracts Infarct Expansion in Ischemic Stroke. | 2021 Feb 5 |
2 |
| 2 |
33460688 | Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. | 2021 Mar 15 |
1 |
| 3 |
34177891 | Immunomodulation Eliminates Inflammation in the Hippocampus in Experimental Autoimmune Encephalomyelitis, but Does Not Ameliorate Anxiety-Like Behavior. | 2021 |
1 |
| 4 |
34484174 | A Novel Radioimmune 99mTc-Labeled Tracer for Imaging Sphingosine 1-Phosphate Receptor 1 in Tumor Xenografts: An In Vitro and In Vivo Study. | 2021 |
2 |
| 5 |
34500564 | ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo. | 2021 Aug 24 |
2 |
| 6 |
34502385 | S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization. | 2021 Aug 31 |
1 |
| 7 |
34603029 | Fingolimod and Diabetic Retinopathy: A Drug Repurposing Study. | 2021 |
3 |
| 8 |
31708456 | Sphingosine-1-phosphate signaling: A novel target for simultaneous adjuvant treatment of triple negative breast cancer and chemotherapy-induced neuropathic pain. | 2020 Jan |
2 |
| 9 |
32301840 | Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. | 2020 Sep 1 |
1 |
| 10 |
32402923 | T cells are the main population in mouse breast milk and express similar profiles of tight junction proteins as those in mammary alveolar epithelial cells. | 2020 Aug |
1 |
| 11 |
32670281 | FTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury. | 2020 |
2 |
| 12 |
32899717 | Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. | 2020 Sep 4 |
3 |
| 13 |
33092620 | Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents. | 2020 Oct 22 |
2 |
| 14 |
30484906 | Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide. | 2019 Mar |
6 |
| 15 |
30802544 | Activation of Sphingosine-1-Phosphate Receptor 1 in the Spinal Cord Produces Mechanohypersensitivity Through the Activation of Inflammasome and IL-1β Pathway. | 2019 Aug |
1 |
| 16 |
30963819 | Sphk1/S1P/S1PR1 Signaling is Involved in the Development of Autoimmune Thyroiditis in Patients and NOD.H-2h4 Mice. | 2019 May |
1 |
| 17 |
31597715 | Anti-donor MHC Class II Alloantibody Induces Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia. | 2019 Dec |
1 |
| 18 |
29140922 | Fingolimod reduces neuropathic pain behaviors in a mouse model of multiple sclerosis by a sphingosine-1 phosphate receptor 1-dependent inhibition of central sensitization in the dorsal horn. | 2018 Feb |
6 |
| 19 |
29205338 | S1P receptor antagonists fingolimod and siponimod do not improve the outcome of experimental autoimmune myasthenia gravis mice after disease onset. | 2018 Mar |
3 |
| 20 |
29945931 | Differential Tolerance to FTY720-Induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of Sphingosine-1-Phosphate Receptor Adaptation. | 2018 Sep |
2 |
| 21 |
30255127 | A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes). | 2018 Sep-Oct |
2 |
| 22 |
27671228 | Neuroprotective effects of fingolimod in mouse models of Parkinson's disease. | 2017 Jan |
2 |
| 23 |
28035084 | Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery. | 2017 Jan 1 |
2 |
| 24 |
28039158 | Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis. | 2017 Mar 1 |
1 |
| 25 |
28082452 | Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension. | 2017 Feb |
1 |
| 26 |
29018225 | S1P1 deletion differentially affects TH17 and Regulatory T cells. | 2017 Oct 10 |
1 |
| 27 |
26589326 | Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. | 2016 Jan 15 |
3 |
| 28 |
27429358 | The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice. | 2016 Sep |
1 |
| 29 |
27699272 | Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to FTY720 during neuroinflammation. | 2016 Jun 16 |
1 |
| 30 |
26795749 | Fingolimod induces neurogenesis in adult mouse hippocampus and improves contextual fear memory. | 2015 Nov 24 |
2 |
| 31 |
24335440 | FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. | 2014 Mar |
3 |
| 32 |
24343820 | S1P lyase in thymic perivascular spaces promotes egress of mature thymocytes via up-regulation of S1P receptor 1. | 2014 May |
2 |
| 33 |
24911000 | Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures. | 2014 |
1 |
| 34 |
25043204 | Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide. | 2014 Sep |
1 |
| 35 |
25309325 | Fingolimod for the treatment of neurological diseases-state of play and future perspectives. | 2014 |
2 |
| 36 |
23073075 | Fingolimod protects cultured cortical neurons against excitotoxic death. | 2013 Jan |
2 |
| 37 |
21632869 | Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. | 2011 Sep |
4 |
| 38 |
19965812 | Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. | 2010 Feb 15 |
1 |
| 39 |
16403835 | Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney. | 2006 Jun |
1 |
| 40 |
16093248 | Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720. | 2005 Nov 4 |
1 |
| 41 |
16118221 | The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity. | 2005 Oct 7 |
1 |
| 42 |
16386642 | FTY720 inhibits TH1-mediated allogeneic humoral immune response. | 2005 Nov |
1 |